756893-81-9

Basic information

• Product Name: [5-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-4-methyl-cyclohex-3-enyl]-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrrol-2-yl]-methanone
• Synonyms: [5-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-4-methyl-cyclohex-3-enyl]-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrrol-2-yl]-methanone
• CAS NO: 756893-81-9
• Molecular Weight: 465.781
• Mol File: 756893-81-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [5-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-4-methyl-cyclohex-3-enyl]-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrrol-2-yl]-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: [5-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-4-methyl-cyclohex-3-enyl]-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrrol-2-yl]-methanone(756893-81-9)
• EPA Substance Registry System: [5-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-4-methyl-cyclohex-3-enyl]-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrrol-2-yl]-methanone(756893-81-9)

Safety Data

• Hazardous Substances Data: 756893-81-9(Hazardous Substances Data)

Upstream product

• 756893-96-6 2-bromo-1-{[2-(trimethylsilyl)ethoxy]methyl}pyrrole 
• 756893-86-4 (1R,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-1-hydroxy-4-methyl-cyclohex-3-enecarboxylic acid methoxy-methyl-amide 
• 852380-66-6 1-<2'-(trimethylsilyl)ethoxymethyl> pyrrole 
• 77-95-2 D-(-)-quinic acid 
• 163217-18-3 (1R,3R,4S,5R)-3-[(tert-butyldimethylsilyl)oxy]-1,4-dihydroxy-6-oxa-bicyclo[3.2.1]octan-7-one 
• 852380-46-2 (1R,3R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-1-hydroxy-4-methylene-6-oxa-bicyclo[3.2.1]octan-7-one 
• 87954-20-9 1-<<(β-trimethylsilyl)ethoxy>methyl>pyrrole 
• 766529-94-6 (1R,3R,5R)-3-[(tert-butyldimethylsilyl)oxy]-1-hydroxy-6-oxa-bicyclo[3.2.1]octane-4,7-dione 
• 756893-85-3 (1R,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-1-hydroxy-4-methyl-cyclohex-3-enecarboxylic acid 
• 665-27-0 1,5-quinide 
• 852380-47-3 (1R,3R,5R)-3-Acetoxy-5-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-4-methylene-cyclohexanecarboxylic acid methyl ester 
• 852380-64-4 (3R,5R)-5-[(tert-butyldimethylsilyl)oxy]-1,3-dihydroxy-4-methylene-cyclohexanecarboxylic acid methyl ester 
• 852380-48-4 (1R,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-1-hydroxy-4-methyl-cyclohex-3-enecarboxylic acid methyl ester 

Downstream Products

• 852380-69-9 ((1R,5R)-1,5-Dihydroxy-4-methyl-cyclohex-3-enyl)-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrrol-2-yl]-methanone 
• 852380-72-4 Acetic acid (1R,5R)-5-hydroxy-2-methyl-5-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrrole-2-carbonyl]-cyclohex-2-enyl ester 
• 852380-70-2 ((1R,5R)-1-Hydroxy-4-methyl-5-triisopropylsilanyloxy-cyclohex-3-enyl)-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrrol-2-yl]-methanone 
• 852380-49-5 (1R,8S,9R,11R)-9-Bromo-3-{5-[6-bromo-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-6-methoxy-pyrazin-2-yl}-8-methoxy-11-methyl-5-(2-trimethylsilanyl-ethoxymethyl)-5-aza-tricyclo[6.3.1.0^2,6]dodeca-2⁽⁶⁾,3-diene-7,10-dione 
• 756893-89-7 (1R,8R,11R)-3-{5-[6-Bromo-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-6-methoxy-pyrazin-2-yl}-8-methoxy-11-methyl-5-(2-trimethylsilanyl-ethoxymethyl)-5-aza-tricyclo[6.3.1.0^2,6]dodeca-2⁽⁶⁾,3-diene-7,10-dione 
• 756894-02-7 (1R,8R,10R,11R)-3-{5-[6-Bromo-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-6-methoxy-pyrazin-2-yl}-10-hydroxy-8-methoxy-11-methyl-5-(2-trimethylsilanyl-ethoxymethyl)-5-aza-tricyclo[6.3.1.0^2,6]dodeca-2⁽⁶⁾,3-dien-7-one 
• 756894-03-8 (1R,8R,11R)-3-{5-[6-Bromo-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-6-methoxy-pyrazin-2-yl}-8-methoxy-11-methyl-5-(2-trimethylsilanyl-ethoxymethyl)-5-aza-tricyclo[6.3.1.0^2,6]dodeca-2⁽⁶⁾,3-diene-7,10-dione 10-oxime 
• 756893-88-6 (1R,8R,10R,11R)-3-{5-[6-Bromo-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-6-methoxy-pyrazin-2-yl}-10-(tert-butyl-dimethyl-silanyloxy)-8-methoxy-11-methyl-5-(2-trimethylsilanyl-ethoxymethyl)-5-aza-tricyclo[6.3.1.0^2,6]dodeca-2⁽⁶⁾,3-dien-7-one 
• 756893-90-0 C₄₆H₅₀BrN₅O₉S₂Si 

Relevant articles and documents

The utility of the classical and oxidative Heck reactions in natural product synthesis: Studies directed toward the total synthesis of dragmacidin F

The syntheses of complex pyrrole-fused [3.3.1] and [3.3.2] bicycles using classical and oxidative Heck cyclizations are described. While both [3.3.1] and [3.2.2] bicyclic products are formed in the classical Heck reaction, the oxidative Heck cyclization r

The total synthesis of (+)-dragmacidin F

The first total synthesis of (+)-dragmacidin F has been accomplished, establishing the absolute configuration of this biologically important, antiviral marine alkaloid. The convergent route described features a palladium-mediated oxidative pyrrole carbocy