75693-15-1

Basic information

• Product Name: 7-Bromo-1,2,3,4-tetrahydronaphthalen-1-ol
• Synonyms: 7-Bromo-1,2,3,4-tetrahydronaphthalen-1-ol
• CAS NO: 75693-15-1
• Molecular Formula: C10H11 Br O
• Molecular Weight: 227.1
• Mol File: 75693-15-1.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-Bromo-1,2,3,4-tetrahydronaphthalen-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Bromo-1,2,3,4-tetrahydronaphthalen-1-ol(75693-15-1)
• EPA Substance Registry System: 7-Bromo-1,2,3,4-tetrahydronaphthalen-1-ol(75693-15-1)

Safety Data

• Hazardous Substances Data: 75693-15-1(Hazardous Substances Data)

Usage

General Description

7-Bromo-1,2,3,4-tetrahydronaphthalen-1-ol, also known as 1-Bromo-7-hydroxytetralin, is a synthetic organic compound with the molecular formula C10H11BrO. It belongs to the class of organic compounds known as tetralins, which are polycyclic aromatic hydrocarbons (PAHs) containing a tetralin moeity, which is a linear tricyclic structure with two benzene rings joined by one saturated carbon ring. The compound includes a hydroxyl group, indicative of its alcohol properties, and a bromine atom, suggesting its potential use in bromination reactions. However, specific information regarding this compound's properties, toxicity, and uses in research or industry appear to be limited, indicating that it may not be widely used or studied.

Upstream product

• 32281-97-3 7-bromo-3,4-dihydro-2H-naphthalen-1-one 

Downstream Products

• 1617524-93-2 C₁₆H₁₄ 
• 32281-97-3 7-bromo-3,4-dihydro-2H-naphthalen-1-one 
• 1049001-69-5 Br^(1-)*C₂₈H₂₅BrP⁽¹⁺⁾ 
• 2717-47-7 1,2-dihydro-6-methylnaphthalene 
• 22531-20-0 6-ethyltetralin 
• 42775-77-9 6-Propyl-tetralin 
• 1680-51-9 6-methyl-1,2,3,4-tetrahydronaphthalene 
• 75693-20-8 7-bromo-1,2-epoxy-1,2,3,4-tetrahydronaphthalene 
• 75693-17-3 bromo-7 dihydro-3,4 naphthalene 

Relevant articles and documents

Development of Novel Phosphino-Oxazoline Ligands and Their Application in Asymmetric Alkynlylation of Benzylic Halides

A new set of stereochemically diverse phosphino-oxazoline ligands derived from simple L-amino acids and 2-(diphenylphosphaneyl)benzoic acid were developed. Those mono anionic tridentated N,N,P-ligands promote the Cu-catalyzed enantioselective radical coupling of terminal alkynes with a broad range of benzylic halides including benzo-fused cyclic α-halides and α-silyl benzyl halides in high yield and excellent enantioselectivity under mild reaction conditions. With multi distinct sites for structural modification, a diverse pool of chiral N,N,P-ligands is readily accessed, allowing for rapid optimization of the ligand structure for a specific substrate. Notably, the enantioselective alkynlylation of benzylic halides bonds in benzo-cyclic molecules has also been realized for the first time.

3-(2,3-DIHYDRO-1H-INDEN-5-YL)PROPANOIC ACID DERIVATIVES AND THEIR USE AS NRF2 REGULATORS

The present invention relates to compounds of Formula (I), and Formula (II), wherein B is benzotriazolyl, phenyl, triazolopyridinyl, or -(CH2)2-triazolyl each of which may be unsubstituted or substituted by 1, 2, or 3 substituents independently chosen from -C1-3 alkyl, -O-C1-3 alkyl, CN, - (CH2)2-O-(CH2)2-OR4 and halo; and D is -C(O)OH, -C(O)NHSO2CH3, -SO2NHC(O)CH3, 5-(trifluoromethyl)-4H-1,2,4-triazol-2-yl, or tetrazolyl; and their use as NRF2 regulators.

NRF2 REGULATORS

The present invention relates to aryl analogs, pharmaceutical compositions containing them and their use as Nrf2 regulators.