75703-63-8

Basic information

• Product Name: 2H-Pyrrole-2,2-dicarboxylic acid, 3,4-dihydro-3-(4-nitrophenyl)-5-phenyl-, diethyl ester
• CAS NO: 75703-63-8
• Molecular Formula: C22H22N2O6
• Molecular Weight: 410.426
• Mol File: 75703-63-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2H-Pyrrole-2,2-dicarboxylic acid, 3,4-dihydro-3-(4-nitrophenyl)-5-phenyl-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyrrole-2,2-dicarboxylic acid, 3,4-dihydro-3-(4-nitrophenyl)-5-phenyl-, diethyl ester(75703-63-8)
• EPA Substance Registry System: 2H-Pyrrole-2,2-dicarboxylic acid, 3,4-dihydro-3-(4-nitrophenyl)-5-phenyl-, diethyl ester(75703-63-8)

Safety Data

• Hazardous Substances Data: 75703-63-8(Hazardous Substances Data)

Upstream product

• 13433-00-6 diethyl aminomalonate hydrochloride 
• 1222-98-6 4-nitrochalcone 

Downstream Products

• 100784-78-9 3-(4-Nitro-phenyl)-5-phenyl-pyrrole-1,2-dicarboxylic acid diethyl ester 
• 100784-69-8 diethyl 3-(p-nitrophenyl)-5-phenyl-2H-pyrrole-2,2-dicarboxylate 
• 100784-87-0 3-(4-Nitro-phenyl)-5-phenyl-1H-pyrrole-2-carboxylic acid ethyl ester 

Relevant articles and documents

The Synthesis and Chemistry of Azolenines. Part 4. Preparation and Rearrangement of some 3,5-Diaryl-2H-pyrrole-2,2-dicarboxylic Esters

Oxidation of diethyl 3,5-diaryl-3,4-dihydro-2H-pyrrole-2,2-dicarboxylates (3) with chloranil in refluxing xylene gives not the 3,5-diaryl-2H-pyrrole-2,2-dicarboxylates (4) as reported by an earlier group, but instead the rearranged, isomeric, 1H-pyrrole-1,2-dicarboxylates (5). 2H-Pyrroles (4) may be obtained from the dihydropyrroles (3) using DDQ in benzene at room temperature; they rearrange to the isomers (5) in boiling xylene via an acyl -sigmatropic shift from carbon to nitrogen, a novel process in the 2H-pyrrole series.Thermal analyses indicate that the rearrangement is concerted with negligible charge separation in the transition state.Other novel 3,5-diaryl-1H-pyrrole-2-carboxylic acid derivatives are described.