75722-64-4

Basic information

• Product Name: Pyridine, 2-(2,4,6-trimethylphenyl)-
• CAS NO: 75722-64-4
• Molecular Formula: C14H15N
• Molecular Weight: 197.28
• Mol File: 75722-64-4.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: Pyridine, 2-(2,4,6-trimethylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2-(2,4,6-trimethylphenyl)-(75722-64-4)
• EPA Substance Registry System: Pyridine, 2-(2,4,6-trimethylphenyl)-(75722-64-4)

Safety Data

• Hazardous Substances Data: 75722-64-4(Hazardous Substances Data)

Upstream product

• 4028-63-1 iodomesitylene 
• 85311-89-3 2-pyridylcopper 
• 109-09-1 2-chloropyridine 
• 2633-66-1 2-mesitylmagnesium bromide 
• 576-83-0 2,4,6-trimethylphenyl bromide 
• 5980-97-2 mesitylboronic acid 
• 109-04-6 2-bromo-pyridine 
• 5029-67-4 2-iodopyridine 
• 108-67-8 1,3,5-trimethyl-benzene 
• 55499-44-0 2,4-dimethylbenzeneboronic acid 
• 914253-86-4 2-(2,4-dimethylphenyl)pyridine 
• 4467-06-5 2-(4-methylphenyl)pyridine 
• 3385-78-2 trimethyl indium 
• 1628-89-3 2-methoxypyridine 

Downstream Products

• 1383625-71-5 methyl 2-{3,5-dimethyl-2-(pyridin-2-yl)phenyl}acetate 
• 1383625-70-4 dimethyl 2,2'-{5-methyl-2-(pyridin-2-yl)-1,3-phenylene}diacetate 

Relevant articles and documents

Highly Chemoselective Deoxygenation of N-Heterocyclic N-Oxides Using Hantzsch Esters as Mild Reducing Agents

Herein, we disclose a highly chemoselective room-temperature deoxygenation method applicable to various functionalized N-heterocyclic N-oxides via visible light-mediated metallaphotoredox catalysis using Hantzsch esters as the sole stoichiometric reductant. Despite the feasibility of catalyst-free conditions, most of these deoxygenations can be completed within a few minutes using only a tiny amount of a catalyst. This technology also allows for multigram-scale reactions even with an extremely low catalyst loading of 0.01 mol %. The scope of this scalable and operationally convenient protocol encompasses a wide range of functional groups, such as amides, carbamates, esters, ketones, nitrile groups, nitro groups, and halogens, which provide access to the corresponding deoxygenated N-heterocycles in good to excellent yields (an average of an 86.8% yield for a total of 45 examples).

Palladium (II) Complexes Containing 2-Phenylpyridine Derivatives: Synthesis, Molecular Structures, and Catalytic Activity for Suzuki–Miyaura Cross-Coupling Reactions

The preparation and characterization of a series of new 2-phenylpyridine derivative ligands consisting of 2-(R) pyridine (R = mesityl (L1), 2,6-dimethylphenyl (L2), o-tolyl (L3), m-tolyl (L4), p-tolyl (L5), o-methoxyphenyl (L6), and p-methoxyphenyl (L7)) and their Pd complexes [PdCl2L2] (L1–L7) is investigated using a combination of X-ray diffraction spectroscopy, GC-MS, and NMR. The crystal structures show that the Pd complexes adopt a square planar geometry, and the monodentate ligand is coordinated through the N donor of the pyridine ring to the Pd atom. The catalytic activities of the synthesized complexes are investigated. The square planar Pd complex trans-[(2-mesitylpy)2PdCl2)] shows a high efficiency in promoting Suzuki-Miyaura cross coupling in an aqueous solvent under aerobic conditions.

Palladium-Catalyzed Electrochemical C-H Alkylation of Arenes

Palladium-catalyzed electrochemical C-H functionalization reactions have emerged as attractive tools for organic synthesis. This process offers an alternative to conventional methods that require harsh chemical oxidants. However, this electrolysis requires divided cells to avoid catalyst deactivation by cathodic reduction. Herein, we report the first example of palladium-catalyzed electrochemical C-H alkylation of arenes using undivided electrochemical cells in water, thereby providing a practical solution for the introduction of alkyl groups into arenes.