75775-36-9

Basic information

• Product Name: Cedrusin
• Synonyms: Cedrusin
• CAS NO: 75775-36-9
• Molecular Formula: C19H22O6
• Molecular Weight: 346.37
• Mol File: 75775-36-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 558.1±50.0 °C(Predicted)
• Appearance: /
• Density: 1.332±0.06 g/cm3(Predicted)
• PKA: 9.79±0.35(Predicted)
• CAS DataBase Reference: Cedrusin(CAS DataBase Reference)
• NIST Chemistry Reference: Cedrusin(75775-36-9)
• EPA Substance Registry System: Cedrusin(75775-36-9)

Safety Data

• Hazardous Substances Data: 75775-36-9(Hazardous Substances Data)

Usage

General Description

Cedrusin is a naturally occurring chemical compound found in the heartwood of cedar trees, specifically the Cedrus genus. It possesses unique antioxidant properties and has been identified as a potential therapeutic agent for various health conditions. Research has shown that cedrusin exhibits anti-inflammatory and antimicrobial activity, making it beneficial for treating inflammatory and infectious diseases. Additionally, cedrusin has demonstrated potential in inhibiting the growth of cancer cells, suggesting its potential as a cancer treatment. Overall, cedrusin shows promise as a bioactive compound with various potential health benefits.

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Relevant articles and documents

Bioactive lignans from the Trunk of Abies holophylla

Six new lignans (1-6) were isolated from the trunk of Abies holophylla MAXIM, together with 11 known lignans (7-17). The structures of 1-7 were elucidated by spectroscopic methods, acid hydrolysis, and use of the modified Mosher's method. The effects of the isolates on nerve growth factor induction in a C6 rat glioma cell line were evaluated. Compounds 6, 7, and 13 showed significant induction of nerve growth factor secretion at concentrations of 10 μM. Compounds 1, 5, 6, and 16 showed moderate inhibitory effects on nitric oxide production in lipopolysaccharide-activated BV-2 cells (IC50 28.5-36.4 μM).

Studies on the constituents of Clematis species. VI. The constituents of Clematis stans SIEB et ZUCC

From the roots of Clematis stans three new oleanane-type triterpenoid saponins named clemastanoside A, B and C, and two new lignan glycosides named clemastanin A and B, have been isolated together with three known triterpenoid saponins, huzhangoside B, C and D, and three known lignan glycosides, (+)-lariciresinol 4-O-β-D-glucopyranoside, (+)-lariciresinol 4'- O-β-D-glucopyranoside and (+)-pinoresinol 4,4'-O-bis-β-D-glucopyranoside. In addition, from the leaves, four new oleanane-type triterpenoid saponins, named clemastanoside D, E, F and G, have been isolated together with five known triterpenoid saponins, hederasaponin B, kizutasaponin K12, huzhangoside B, sieboldianoside B and huzhangoside D, and three known flavonoids, isoquercitrin, ratin and quercetin 3-O-β-D-glucuronopyranoside. The structures of the new compounds were elucidated based on chemical and physicochemical evidence as follows: clemastanoside A, 3-O-β-D- ribopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl oleanolic acid 28-O-(4-O-acetyl)-α-L-rhamnopyranosyl-(1→4)-β-D- glucopyranosyl-(1→6)-β-D-glucopyranosyl ester (terminal rhamnosyl 4-O- acetate of huzhangoside B); clemastanoside B and C, 3-O-β-D-xylopyranosyl- and 3-O-β-D-ribopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-β-D- galactopyranosyl oleanolic acid 28-O-α-L-rhamnopyranosyl-(1→4)-β-D- glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, respectively; clemastanoside D, 3-O-β-D-ribopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L- arabinopyranosyl hederagenin 28-O-β-D-glucopyranosyl ester; clemastanoside E, F and G, terminal rhamnosyl 4-O-, 3-O- and 2-O-acetate of 3-O-β-D- ribopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin 28-O-α-L-rhamno-pyranosyl-(1→4)-β-D-glucopyranosyl-(1→6]-β- D-glucopyranosyl ester, respectively; clemastanin A, (7S,8R)-3-methoxy- 3',4,9,9'-tetrahydroxy-4',7-epoxy-5',8-lignan 3'-O-β-D-glucopyranoside; clemastanin B, (+)-lariciresinol 4,4'-O-bis-β-D-glucopyranoside.