7579-74-0Relevant articles and documents
Synchronous Ar-F and Ar-Sn bond formation through fluorostannylation of arynes
Yoshida, Hiroto,Yoshida, Ryuma,Takaki, Ken
, p. 8629 - 8632 (2013)
An aryne insertion into the F-Sn bond of tributyltin fluoride leads to the synchronous formation of Ar-F and Ar-Sn bonds to afford diverse 2-fluoroarylstannanes straightforwardly. The formal total synthesis of flurbiprofen by using a fluorostannylation product is also reported. Copyright
TYK2 INHIBITORS AND USES THEREOF
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Paragraph 001223; 001224, (2015/09/28)
The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
Convenient syntheses of aryl and perfluoroaryl trichlorogermanes and germatranes via an organotin route
Kultyshev, Roman G.,Prakash, G.K. Surya,Olah, George A.,Faller, Jack W.,Parr, Jonathan
, p. 3184 - 3188 (2008/10/09)
Aryl- and (perfluoroaryl)trichlorogermanes ArGeCl3(Ar = C 6H5, 2-FC6H4, 3,5-(CF 3)2C6H3, C6F5, 2,3,5,6-F4C5N) are easily obtained in 60-80% yields from the corresponding tributyl-stannanes and GeCl4 (1:1) at 150 °C in the absence of a solvent. Although the tin-to-germanium transmetalation of C6F5 group is sluggish, it is facilitated by addition of 1-2 mol % AIBN (2,2′-azobis(isobutyronitrile)).
