758698-79-2

Basic information

• Product Name: 2-amino-N-(2-diisopropylamino-ethyl)-3-phenyl-propionamide
• Synonyms: 2-amino-N-(2-diisopropylamino-ethyl)-3-phenyl-propionamide
• CAS NO: 758698-79-2
• Molecular Weight: 291.437
• Mol File: 758698-79-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-amino-N-(2-diisopropylamino-ethyl)-3-phenyl-propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-N-(2-diisopropylamino-ethyl)-3-phenyl-propionamide(758698-79-2)
• EPA Substance Registry System: 2-amino-N-(2-diisopropylamino-ethyl)-3-phenyl-propionamide(758698-79-2)

Safety Data

• Hazardous Substances Data: 758698-79-2(Hazardous Substances Data)

Upstream product

• 121-05-1 N',N'-diisopropyl-ethane-1,2-diamine 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 758698-76-9 [(S)-1-(2-diisopropylamino-ethyl-carbamoyl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Novel glycine transporter type-2 reuptake inhibitors. Part 1: α-amino acid derivatives

A variety of α-amino acid derivatives were prepared as glycine transport inhibitors and their ability to block the uptake of [ 14C]-glycine in COS7 cells transfected with human glycine transporter-2 (hGlyT-2) was evaluated. An array of substituents at the chiral center was studied and overall, L-phenylalanine was identified as the preferred amino acid residue. Compounds prepared from L-amino acids were more potent GlyT-2 inhibitors than analogs derived from the corresponding D-amino acids. Introducing an achiral amino acid such as glycine, or incorporating geminal substitution in the α-position, led to a significant reduction in GlyT-2 inhibitory properties.