75949-45-0Relevant articles and documents
Synthesis and characterization of a series of isomeric oxotechnetium(V) diamido dithiolates
Brenner, David,Davison, Alan,Lister-James, John,Jones, Alun G.
, p. 3793 - 3797 (2008/10/08)
The diamido dithiolato technetium complexes [TcO(SCH2CONCH2CONCH2CH2S)] - and [TcO(SCH2CH2NCO)2]- have been prepared both via dithionite reduction of TcO4- and by ligand exchange from [TcO(OCH2CH2O)2]-. The synthesis and characterization of the complexes and their precursor ligands are presented. The highly stereoselective deuterium exchange of the active methylenes of [TcO(SCH2CONCH2CONCH2CH2S)] - is discussed. The application of this chemistry to radiopharmaceuticals is considered.