7596-74-9

Basic information

• Product Name: 3-(1H-BENZIMIDAZOL-2-YL)ANILINE
• Synonyms: 3-(1H-benzimidazol-2-yl)aniline(SALTDATA: FREE);3-(1H-benzo[d]iMidazol-2-yl)benzenaMine;3-(1H-benzo[d]imidazol-2-yl)aniline
• CAS NO: 7596-74-9
• Molecular Formula: C₁₃H₁₁N₃
• Molecular Weight: 209.25
• Mol File: 7596-74-9.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 482.5°C at 760 mmHg
• Flash Point: 277.3°C
• Appearance: /
• Density: 1.286g/cm³
• Vapor Pressure: 1.81E-09mmHg at 25°C
• Refractive Index: 1.737
• CAS DataBase Reference: 3-(1H-BENZIMIDAZOL-2-YL)ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1H-BENZIMIDAZOL-2-YL)ANILINE(7596-74-9)
• EPA Substance Registry System: 3-(1H-BENZIMIDAZOL-2-YL)ANILINE(7596-74-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 7596-74-9(Hazardous Substances Data)

Usage

General Description

3-(1H-benzimidazol-2-yl)aniline is a chemical compound with the molecular formula C13H11N3. 3-(1H-BENZIMIDAZOL-2-YL)ANILINE is a derivative of aniline and benzimidazole, and it is commonly used in pharmaceutical and research applications. It has the potential to be used as a building block in the synthesis of various biologically active molecules and pharmaceutical compounds. Additionally, it may have uses in the development of new materials in the field of organic chemistry. The chemical structure of 3-(1H-benzimidazol-2-yl)aniline consists of a benzimidazole ring fused to an aniline moiety, which gives it unique properties and potential reactivity in various chemical processes.

InChI:InChI=1/C13H11N3/c14-10-5-3-4-9(8-10)13-15-11-6-1-2-7-12(11)16-13/h1-8H,14H2,(H,15,16)

Upstream product

• 39145-59-0 o-phenylenediamine hydrochloride 
• 95-54-5 1,2-diamino-benzene 
• 1709-44-0 m-aminobenzaldehyde 
• 121-92-6 3-nitrobenzoic acid 
• 5969-92-6 N-o-aminophenyl m-nitrobenzamide 
• 99-61-6 3-nitro-benzaldehyde 
• 65953-23-3 3-nitro-N-[2-[(3-nitrobenzoyl)amino]phenyl]benzamide 
• 121-90-4 m-nitrobenzoic acid chloride 
• 88-74-4 2-nitro-aniline 
• 7647-01-0 hydrogenchloride 
• 99847-32-2 3-nitro-benzoic acid-(2-nitro-anilide) 
• 70086-34-9 2',3-diaminobenzanilide 
• 99-05-8 meta-aminobenzoic acid 
• 15456-62-9 2-(3-nitrophenyl)-1H-benzimidazole 

Downstream Products

• 76618-08-1 2-Methyl-3--6-bromo-quinazolin(3H)-4-one 
• 76617-99-7 2-Phenyl-3-quinazolin(3H)-4-one 
• 76618-06-9 2-Phenyl-3--6-iodo-q Quinazolin(3H)-4-one 
• 76618-04-7 2-Phenyl-3--6,8-dibromo-quinazolin(3H)-4-one 
• 76618-11-6 2-Methyl-3--6,8-dibromo-quinazolin(3H)-4-one 
• 130713-38-1 Diethyl <3-(2-benzimidazolyl)phenyl>aminomethylenemalonate 
• 76618-02-5 2-Phenyl-3--6-bromo-quinazolin(3H)-4-one 
• 1031126-38-1 N-[3-(1H-benzimidazol-2-yl)phenyl]furan-3-carboxamide 
• 496913-64-5 N-[3-(1H-benzoimidazol-2-yl)-phenyl]-2-(2-thienyl)acetamide 
• 333395-09-8 N-[3-(1H-benzimidazol-2-yl)phenyl]-2,2-dimethylpropanamide 
• 314029-69-1 N-[3-(1H-benzimidazol-2-yl)phenyl]-3-chlorobenzamide 
• 420102-99-4 N-[3-(1H-1,3-benzodiazol-2-yl)phenyl]-3-methoxybenzamide 
• 477486-40-1 N-[3-(1H-benzimidazol-2-yl)phenyl]-3-trifluoromethylbenzamide 
• 404831-36-3 N-[3-(1H-benzimidazol-2-yl)phenyl]-2-methylbenzamide 

Relevant articles and documents

Design and synthesis of 2-phenyl benzimidazole derivatives as VEGFR-2 inhibitors with anti-breast cancer activity

Three new series of 2-phenyl benzimidazole-based derivatives were designed, synthesized, and evaluated for their in vitro cytotoxic activity against breast cancer (MCF-7) cell lines. Three compounds 8, 9, and 15 showed high cytotoxic activities, with ICs

Novel Phenolic Compounds as Potential Dual EGFR and COX-2 Inhibitors: Design, Semisynthesis, in vitro Biological Evaluation and in silico Insights

Introduction: Epidermal growth factor receptor (EGFR) inhibition is an imperative therapeutic approach targeting various types of cancer including colorectal, lung, breast, and pancreatic cancer types. Moreover, cyclooxygenase-2 (COX-2) is frequently over

Benzimidazole derivative and application thereof

The invention relates to the field of medicinal chemistry, in particular to a 3-(1H-benzo [d] imidazole-2-yl) aniline derivative with alpha-glucosidase inhibition activity, and the structural generalformula of the derivative is shown in the specification.