76055-02-2

Basic information

• Product Name: 2-benzyloxycarbonylamino-N-(2-pyridyl)acetamidine hydrochloride
• CAS NO: 76055-02-2
• Molecular Weight: 320.779
• Mol File: 76055-02-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-benzyloxycarbonylamino-N-(2-pyridyl)acetamidine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyloxycarbonylamino-N-(2-pyridyl)acetamidine hydrochloride(76055-02-2)
• EPA Substance Registry System: 2-benzyloxycarbonylamino-N-(2-pyridyl)acetamidine hydrochloride(76055-02-2)

Safety Data

• Hazardous Substances Data: 76055-02-2(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 3589-41-1 phenylmethyl cyanomethylcarbamate 
• 504-29-0 2-aminopyridine 
• 51030-44-5 ethyl 2-benzyloxycarbonylaminoacetimidate hydrochloride 

Relevant articles and documents

Purines, Pyrimidines, and Imidazoles. Part 54. Interconversion of Some Intermediates in the de novo Biosynthesis of Purine Nucleotides

Ethyl and benzyl 5-amino-1-(2-pyridyl)imidazole-4-carboxylates, obtained from ethyl or benzyl α-amino-α-cyanoacetate, respectively, and ethyl formimidate hydrochloride followed by 2-aminopyridine, were converted into 5-amino-1-(2-pyridyl)imidazole-4-carboxylic acid which was decarboxylated in situ to 5-amino-1-(2-pyridyl)imidazole.Reaction of 2-N-formylamino-N-(2-pyridyl)acetamide with ammonia and ammonium chloride gave 5-aminoimidazole and a similar reaction with the nucleotide 2-N-formylglicineamide ribotide similarly gave evidence for aminoimidazole formation. 4-Cyano-5- imidazolone, prepared by reaction of 2-cyano-N-formylacetamide with nitrous acid and reduction of the hydroxyimino derivative so produced, with ammonia and ammonium sulphite at 100 deg C, gave 5-aminoimidazole-4-carboxamide.Implications of the reactions involved are discussed.