76066-78-9

Basic information

• Product Name: 2-hydroxy-1,3-diphenylquinolin-4(1H)-one
• CAS NO: 76066-78-9
• Molecular Formula: C₂₁H₁₅NO₂
• Molecular Weight: 313.3493
• Mol File: 76066-78-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 478.3°C at 760 mmHg
• Flash Point: 243°C
• Density: 1.314g/cm³
• Vapor Pressure: 5.9E-10mmHg at 25°C
• Refractive Index: 1.7
• CAS DataBase Reference: 2-hydroxy-1,3-diphenylquinolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-1,3-diphenylquinolin-4(1H)-one(76066-78-9)
• EPA Substance Registry System: 2-hydroxy-1,3-diphenylquinolin-4(1H)-one(76066-78-9)

Safety Data

• Hazardous Substances Data: 76066-78-9(Hazardous Substances Data)

Upstream product

• 122-39-4 diphenylamine 
• 83-13-6 diethyl 2-phenylmalonate 
• 773837-37-9 sodium cyanide 
• 144603-36-1 3-chloro-1,3-diphenyl-1H,3H-quinoline-2,4-dione 
• 1432733-46-4 1,2-dihydro-1,3-diphenyl-2-oxo-quinolin-4-yl dihydrogen phosphate 
• 521980-40-5 1,3-diphenyl-2,4-dioxo-1,2,3,4-tetrahydroquinolin-3-yl thiocyanate 

Downstream Products

• 83609-80-7 4-chloro-1,3-diphenylquinolin-2(1H)-one 
• 84261-45-0 3-Hydroxy-1,3-diphenyl-1H-quinoline-2,4-dione 
• 146765-07-3 1,3-diphenyl-3-nitroquinoline-2,4-(1H,3H)-dione 
• 76870-57-0 5-Phenyl-5,6-dihydro-benzofuro<3,2-c>chinolin-6-on 
• 83609-83-0 4-Benzylidenamino-1,3-diphenyl-chinolin-2(1H)-on 
• 83609-73-8 5,11-Diphenyl-isochinolino<4,3-c>chinolin-6(5H)-on 
• 110216-92-7 1,3-Diphenyl-4-tosyloxy-2(1H)-chinolon 
• 521980-40-5 1,3-diphenyl-2,4-dioxo-1,2,3,4-tetrahydroquinolin-3-yl thiocyanate 
• 83609-77-2 4-Benzylamino-1,3-diphenyl-chinolin-2(1H)-on 
• 83609-68-1 4-Amino-1,3-diphenyl-chinolin-2(1H)-on 
• 144603-36-1 3-chloro-1,3-diphenyl-1H,3H-quinoline-2,4-dione 
• 1432733-46-4 1,2-dihydro-1,3-diphenyl-2-oxo-quinolin-4-yl dihydrogen phosphate 

Relevant articles and documents

Reaction of Tertiary 2-Chloroketones with Cyanide Ions: Application to 3-Chloroquinolinediones

3-Chloroquinoline-2,4-diones react with cyanide ions in dimethyl formamide to give 3-cyanoquinoline-2,4-diones in small yields due to the strong hindrance of the substituent at the C-3 atom. Good yields can be achieved if the substituent at this position

Palladium-catalyzed double C-H functionalization of 2-aryl-1,3-dicarbonyl compounds: A facile access to alkenylated benzopyrans

The present study reports the development of a palladium-catalyzed oxidative annulation/nucleophilic substitution sequence affording a library of alkenylated benzopyrans using 2-aryl-1,3-dicarbonyl compounds and allylic acetate. The process is compatible

Novel tandem hydration/cyclodehydration of α-thiocyanatoketones to 2-oxo-3-thiazolines. Application, to thiazolo[5,4-c]quinoline-2}4(3aH,5H)-dione synthesis

Novel tandem hydration of α-thiocyanatoketones to thiocarbamates followed by in situ cyclodehydration to fused 2-oxo-3-thiazolines is described. The reaction is applied to the synthesis of [1,3]-thiazolo[5,4-c]quinoline-2, 4(3aH,5H)-diones (4). Concentrated sulfuric acid was found to be critical for the reaction as both corresponding 2,3-dioxo-1,2,3,4-tetrahydroquinolin-3-yl thiocyanates (2) and S-(2,4-dioxo-1,2,3,4-tetrahydroquinolin-3-yl) thiocarbamates (3) rapidly hydrolyze in the presence of water to 4-hydroxyquinolin-2(1H)-ones (1).