761-01-3 Usage
Description
SULFUR TRIOXIDE-TRIETHYLAMINE COMPLEX is a chemical compound that serves as a versatile reagent in the synthesis of various pharmaceutical agents and compounds. It is known for its ability to facilitate the formation of persulfated glycosides or flavonoids, which have potential applications in anticoagulant and antiplatelet therapies.
Uses
Used in Pharmaceutical Industry:
SULFUR TRIOXIDE-TRIETHYLAMINE COMPLEX is used as a reagent for the synthesis of anticoagulant and antiplatelet persulfated glycosides or flavonoids containing an oligopolysulfated moiety. These compounds have potential therapeutic applications in preventing blood clot formation and improving cardiovascular health.
Used in Anticancer Drug Development:
SULFUR TRIOXIDE-TRIETHYLAMINE COMPLEX is used as a reagent for the synthesis of narciclasine derivatives, which are being investigated for their potential as anticancer agents. These derivatives may exhibit cytotoxic effects on cancer cells and could be further developed into novel therapeutic agents for cancer treatment.
Used in Colon-Specific Drug Delivery:
SULFUR TRIOXIDE-TRIETHYLAMINE COMPLEX is used as a reagent for the synthesis of sulfate-conjugated methylprednisolone and dexamethasone 21-sulfate sodium. These compounds are designed as colon-specific prodrugs, allowing for targeted drug delivery to the colon and reducing systemic side effects.
Used in Heparin Research:
SULFUR TRIOXIDE-TRIETHYLAMINE COMPLEX is used as a reagent for the synthesis of tetrasaccharide substrates of heparanase by glycosylation of disaccharides. This process aids in the study of heparanase enzymes and their role in various biological processes.
Used in Analysis of Heparin-Protein Interactions:
SULFUR TRIOXIDE-TRIETHYLAMINE COMPLEX is used as a reagent for the synthesis of synthetic heparin oligosaccharide microarrays. These microarrays are utilized for the analysis of heparin-protein interactions, which can provide valuable insights into the development of new heparin-based therapeutic agents and diagnostic tools.
Check Digit Verification of cas no
The CAS Registry Mumber 761-01-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,6 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 761-01:
(5*7)+(4*6)+(3*1)+(2*0)+(1*1)=63
63 % 10 = 3
So 761-01-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H15N.O3S/c1-4-7(5-2)6-3;1-4(2)3/h4-6H2,1-3H3;
761-01-3Relevant articles and documents
Novel Burgess reagent mediated C-to-N aryl migration reaction in nitrones
Sajitha,Prathapan,Unnikrishnan
, p. 44689 - 44691 (2014/12/10)
Nitrones undergo useful transformations with Burgess reagent. The reaction ostensibly involves a [3 + 2] annulation across a σ-bond followed by rearrangement involving C-to-N aryl migration. On the basis of available experimental evidence, plausible mechanisms for the rearrangement and the overall conversion have been proposed.
