761377-71-3Relevant articles and documents
95. Design and Synthesis of Potent Macrocyclic Benzolactam Growth Hormone Secretagogues
DeVita, Robert J.,Frontier, Alison J.,Schoen, William R.,Wyvratt, Matthew J.,Fisher, Michael H.,Cheng, Kang,Chan, Wanda W.-S.,Butler, Bridget S.,Smith, Roy G.
, p. 1244 - 1259 (2007/10/03)
The synthesis of a variety of potent macrocyclic growth hormone secretagogues, i.e. 5, 9, 12, and 20-22, based on the known lead structure L-692,429 (1) is described. These conformationally constrained growth hormone secretagogues were prepared by joining