76224-57-2Relevant articles and documents
SYNTHESIS OF (+)-AVENIC ACID A
Ohfune, Yasufumi,Nomoto, Kyosuke
, p. 827 - 828 (1981)
Avenic acid A (2), the metal chelator excreted from oat root and the factor which is considered to be directly involved in the uptake and transport of iron and other elements, has been synthesized efficiently from L-Nhomoserine
SYNTHESIS OF AVENIC ACID A AND 2'-DEOXYMUGIENIC ACID, AMINO ACIDS POSSESSING AN IRON CHELATING ACTIVITY
Fushiya, Shinji,Sato, Yoshikazu,Nakatsuyama, Shuichi,Kanuma, Norio,Nozoe, Shigeo
, p. 909 - 912 (2007/10/02)
Avenic acid A (1), an amino acid derivative possessing an iron chelating activity and excreted from the root of Avena sativa L. was synthesized in optically active form by successive reductive coupling of protected L-aspartic β-semialdehyde and L-malic semialdehyde with L-homoserine lactone. 2'-Deoxymugineic acid (2), a related substance was also synthesized by the same method by which the stereostructure of this amino acid derivative was proved to be 2(S), 3'(S),3''(S)-N--azetidine-2-carboxylic acid.