76261-60-4

Basic information

• Product Name: 2,3-bis(methylsulfanyl)quinoxaline
• Synonyms: 2,3-bis(methylsulfanyl)quinoxaline
• CAS NO: 76261-60-4
• Molecular Formula: C10H10N2S2
• Molecular Weight: 222.3298
• Mol File: 76261-60-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,3-bis(methylsulfanyl)quinoxaline(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-bis(methylsulfanyl)quinoxaline(76261-60-4)
• EPA Substance Registry System: 2,3-bis(methylsulfanyl)quinoxaline(76261-60-4)

Safety Data

• Hazardous Substances Data: 76261-60-4(Hazardous Substances Data)

Usage

General Description

2,3-bis(methylsulfanyl)quinoxaline is a chemical compound that is also known as DMDBS or Methoxine. It is a heterocyclic organic compound with the molecular formula C10H10N2S2. It is commonly used in the production of organic semiconductors and has been studied for its potential use in optoelectronic devices and organic photovoltaic cells. Its unique chemical structure and properties make it a promising candidate for various applications in the field of materials science and electronics. Additionally, it has been investigated for its potential use as a pharmaceutical intermediate in the synthesis of certain drugs.

Upstream product

• 21659-28-9 3-mercaptoquinoxalin-2-yl carbamimidothioate hydrochloride 
• 74-88-4 methyl iodide 
• 1199-03-7 quinoxaline-2,3-dithiole 
• 15804-19-0 quinoxaline-2,3-dione 
• 2213-63-0 2,3-dichloroquinoxaline 
• 1199-03-7 1,4-dihydro-quinoxaline-2,3-dithione 
• 77-78-1 dimethyl sulfate 

Relevant articles and documents

Antitumoural sulphur and selenium heteroaryl compounds: Thermal characterization and stability evaluation

The physicochemical properties of a compound play a crucial role in the cancer development process. In this context, polymorphism can become an important obstacle for the pharmaceutical industry because it frequently leads to the loss of therapeutic effectiveness of some drugs. Stability under manufacturing conditions is also critical to ensure no undesired degradations or transformations occur. In this study, the thermal behaviour of 40 derivatives of a series of sulphur and selenium heteroaryl compounds with potential antitumoural activity were studied. In addition, the most promising cytotoxic derivatives were analysed by a combination of differential scanning calorimetry, X-ray diffraction and thermogravimetric techniques in order to investigate their polymorphism and thermal stability. Moreover, stability under acid, alkaline and oxidative media was tested. Degradation under stress conditions as well as the presence of polymorphism was found for the compounds VA6E and VA7J, which might present a hurdle to carrying on with formulation. On the contrary, these obstacles were not found for derivative VA4J.

Efficient diverse approach for quinoxaline-derived glycosylated and morphinylated analogs

Sulfanyl-glycosides have been synthesized by reaction of 2,3-dimercaptoquinoxaline (1) with acetohalo sugars in presence of base to give the thioglycosides-derived quinoxalines 5-7 and 9. Similarly, the acyclic analogs 23-26 were prepared by coupling of 1 with different acyclo-alkylating agents. The preparation of 3-morpholinyl-quinoxalines 10 and 11 allowed the synthesis of 3-glycosylsulfanyl-2-morpholinyl-quinoxalines 12-14 and 17 as well as the acyclic analogs 27-29. Microwave irradiation of the reactants turned out to be preferred over the conventional method for achieving the synthetic goals. This study made an available venue to the synthesis of diverse quinoxaline derivatives.