76288-44-3

Basic information

• Product Name: 5-Hydroxy-2-(4-hydroxy-phenyl)-8,8-dimethyl-7,8-dihydro-6H-pyrano[3,2-g]chromen-4-one
• CAS NO: 76288-44-3
• Molecular Weight: 338.36
• Mol File: 76288-44-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Hydroxy-2-(4-hydroxy-phenyl)-8,8-dimethyl-7,8-dihydro-6H-pyrano[3,2-g]chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Hydroxy-2-(4-hydroxy-phenyl)-8,8-dimethyl-7,8-dihydro-6H-pyrano[3,2-g]chromen-4-one(76288-44-3)
• EPA Substance Registry System: 5-Hydroxy-2-(4-hydroxy-phenyl)-8,8-dimethyl-7,8-dihydro-6H-pyrano[3,2-g]chromen-4-one(76288-44-3)

Safety Data

• Hazardous Substances Data: 76288-44-3(Hazardous Substances Data)

Upstream product

• 520-36-5 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 
• 870-63-3 prenyl bromide 
• 115-18-4 2-methyl-3-buten-2-ol 
• 83171-42-0 4,6-dimethoxy-2-(4'-methoxybenzoyloxy)acetophenone 
• 76288-41-0 1-(4'-methoxyphenyl)-3-(2''-hydroxy-3'',6''-dimethoxyphenyl)-1,3-propanedione 
• 100-07-2 4-methoxy-benzoyl chloride 
• 5631-70-9 4',5,7-trimethoxyflavone 
• 90-24-4 2-hydroxy-4,6-dimethoxyacetophenone 

Relevant articles and documents

Prenylation of Apigenin

Apigenin (I) on prenylation with 2-methylbut-3-ene-2-ol affords two major and four minor products.The major products are characterized as 6-C-prenylapigenin (II) and 5,4'-dihydroxy-6'',6''-dimethyl-4'',5''-dihydropyranoflavone (III) and the minor products as 7-O-prenylapigenin (IV), 5,4'-dihydroxy-6'',6''-dimethyl-5''-C-prenyl-4'',5''-dihydropyranoflavone (V), 5,4'-dihydroxy-6'',6''-dimethyl-4'',5''-dihydropyranoflavone (VI) and 5,4'-dihydroxy-6'',6''-dimethyl-5''-C-prenyl-4'',5''-dihydropyranoflavone (VII).Prenylation of apigenin with prenyl bromide in presence of methanolic sodium methoxide yields two major products, identified as 6,8-di(C-prenyl)apigenin (VIII) and 6-C-prenylapigenin (II), and four minor products, viz. 7,4'-di-O-prenylapigenin (IX), 8-C-prenyl-5,4'-dihydroxy-6'',6''-dimethyl-4'',5''-dihydropyranoflavone (X), 7-O-prenylapigenin (IV) and 5,4'-dihydroxy-6'',6''-dimethyl-4'',5''-dihydropyranoflavone (VI).Apigenin has been synthesized by a new route in a better yield.