76293-13-5

Basic information

• Product Name: 2,4-dimethylthioxanthen-9-one
• Synonyms: 2,4-dimethylthioxanthen-9-one;2-(4-sulfophenyl)-3,4-dihydro-5-methyl-Pyrazol-3-one;2,4-Dimethyl-9H-thioxanthen-9-one;2,4-Dimethylthioxantone
• CAS NO: 76293-13-5
• Molecular Formula: C₁₅H₁₂OS
• Molecular Weight: 240.32018
• EINECS: 278-414-8
• Mol File: 76293-13-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 408°Cat760mmHg
• Flash Point: 229.8°C
• Appearance: /
• Density: 1.234g/cm³
• Vapor Pressure: 7.23E-07mmHg at 25°C
• Refractive Index: 1.658
• CAS DataBase Reference: 2,4-dimethylthioxanthen-9-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dimethylthioxanthen-9-one(76293-13-5)
• EPA Substance Registry System: 2,4-dimethylthioxanthen-9-one(76293-13-5)

Safety Data

• Hazardous Substances Data: 76293-13-5(Hazardous Substances Data)

Usage

General Description

2,4-Dimethylthioxanthen-9-one, also known as thioxanthone, is a chemical compound with the molecular formula C15H10OS. It is a yellow-colored solid that is insoluble in water but soluble in organic solvents. Thioxanthone is commonly used as a photoinitiator in the production of various polymer materials, where it initiates the crosslinking or polymerization reactions when exposed to ultraviolet light. It is also used in the synthesis of dyes and pharmaceutical compounds. Thioxanthone is known for its strong absorption of UV light and is often used in the formulation of inks, coatings, and adhesives in the printing and packaging industries. Additionally, it has potential applications in medicinal chemistry and organic synthesis due to its versatile reactivity and structural properties.

InChI:InChI=1/C15H12OS/c1-9-7-10(2)15-12(8-9)14(16)11-5-3-4-6-13(11)17-15/h3-8H,1-2H3

Upstream product

• 119-80-2 2,2'-dithiobenzoic acid 
• 108-38-3 m-xylene 
• 13616-82-5 2,4-dimethyl-thiophenol 
• 108-88-3 toluene 
• 118-91-2 ortho-chlorobenzoic acid 
• 113296-91-6 2-(2,4-dimethylphenylthio)benzoic acid 
• 147-93-3 Thiosalicylic acid 

Downstream Products

• 73839-33-5 trans-2,4,9-trimethylthioxanthene N-(p-toluenesulfonyl)sulfilimine 
• 73839-38-0 2,4,9-trimethyl-9-(N-p-toluenesulfonamido)thioxanthene 

Relevant articles and documents

Novel thioxanthone compound synthesis method

The invention belongs to the technical field of synthesis and discloses a novel thioxanthone compound synthesis method. The method includes steps: sequentially adding alkali and o-chlorobenzoic acid into a solvent, stirring to enable neutralization reaction, dropwise adding alkyl thiophenol into a reaction system after heat release stops in neutralization reaction, heating to 120-220 DEG C, keeping the temperature, and performing etherification reaction for 8-12h; after etherification reaction is finished, cooling to the room temperature, starting tail gas absorption, keeping the pressure of the reaction system in a range from -0.03 to -0.08Mpa, dropwise adding concentrated sulfuric acid into etherified liquid, performing thermal reaction at 20-60 DEG C for 3-7h, and dropwise adding a dehydrating agent into the reaction system in the reaction process to remove water generated in cyclization reaction; adding water into reaction liquid after reaction, stirring, standing for layering, andsubjecting organic supernatant to solvent removal and recrystallization to obtain a target product namely a thioxanthone compound. The total product yield is high, sulfuric acid solution containing potassium hydrogen sulfate is a byproduct, and easiness in treatment and recovery and environmental friendliness are realized.

Methods of treating conditions associated with an Edg-7 receptor

In one aspect, the present invention provides a method for modulating an Edg-7 receptor mediated biological activity in a cell. A cell expressing the Edg-7 receptor is contacted with a modulator of the Edg-7 receptor which is capable of modulating an Edg-7 receptor mediated biological activity. In another aspect, the present invention provides a method for modulating an Edg-7 receptor mediated biological activity in a subject. A therapeutically effective amount of a modulator of the Edg-7 receptor is administered to the subject.

Dimethylthioxanthones formed by condensation of 2-mercaptobenzoic acid with o-, or m-xylene in sulfuric acid

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