76323-09-6

Basic information

• Product Name: 2,5-dihydroxydibenzyloxymethane
• Synonyms: 2,5-dihydroxydibenzyloxymethane
• CAS NO: 76323-09-6
• Molecular Weight: 256.258
• Mol File: 76323-09-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,5-dihydroxydibenzyloxymethane(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-dihydroxydibenzyloxymethane(76323-09-6)
• EPA Substance Registry System: 2,5-dihydroxydibenzyloxymethane(76323-09-6)

Safety Data

• Hazardous Substances Data: 76323-09-6(Hazardous Substances Data)

Upstream product

• 93-58-3 benzoic acid methyl ester 
• 490-78-8 2,5-Dihydroxyacetophenone 
• 76323-08-5 1-acetyl-1,3-bis(benzoyloxy)benzene 

Downstream Products

• 808784-13-6 C₂₂H₁₃ClO₄ 
• 691392-48-0 C₂₂H₁₃NO₆ 
• 808784-07-8 C₂₃H₁₆O₄ 
• 808784-08-9 2'-phenyl-4'-benzopyrone-6'-yl-4-methylbenzoate 
• 808784-16-9 C₂₂H₁₃BrO₄ 
• 808784-01-2 C₂₃H₁₆O₄ 
• 808784-15-8 C₂₂H₁₃ClO₄ 
• 577-85-5 3-hydroxyflavone 
• 22812-29-9 2-phenyl-3-benzoyloxy-4-oxo-4H-1-benzopyran 
• 6665-83-4 6-hydroxyflavone 

Relevant articles and documents

Design, synthesis, and biological evaluation of novel 4H-chromen-4-one derivatives as antituberculosis agents against multidrug-resistant tuberculosis

A series of 4H-chromen-4-one derivatives obtained by scaffold morphing of the benzofuran compound, TAM16, were tested for antitubercular activity. Compound 8d was active against drug-sensitive and multidrug-resistant tuberculosis. A preliminary druggability evaluation showed that compound 8d displayed favorable mouse and human microsomal stability, low cytotoxicity, and acceptable oral bioavailability. An in vivo study indicated that compound 8d exhibited modest efficacy in an acute mouse model of TB after 3 weeks of treatment. Thus, 8d is a promising antituberculosis lead compound.