76330-71-7 Usage
Description
Altanserin is a chemical compound with the chemical formula C21H26ClFNO and is classified as a selective antagonist of the 5-HT2A receptor. It is a yellowish solid and is used as an intermediate in organic synthesis. Altanserin has been widely studied for its potential applications in various fields due to its unique chemical properties and receptor specificity.
Uses
Used in Pharmaceutical Industry:
Altanserin is used as a pharmaceutical intermediate for the development of drugs targeting the 5-HT2A receptor. Its application is primarily due to its ability to selectively bind to this receptor, which is implicated in various neurological and psychiatric disorders.
Used in Research and Development:
In the field of research, Altanserin is used as a research tool to study the role of the 5-HT2A receptor in different biological processes. It helps scientists understand the receptor's function and its involvement in various diseases, which can lead to the development of new therapeutic strategies.
Used in Organic Synthesis:
Altanserin is also used as an intermediate in organic synthesis, where it can be further modified or used as a building block to create more complex molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Biological Activity
Potent and selective 5-HT 2A receptor antagonist (K i values are 0.13, 4.55, 40, 62 and 1570 nM at 5-HT 2A , α 1 , 5-HT 2C , D 2 and 5-HT 1A respectively). Centrally active following systemic administration in vivo .
Check Digit Verification of cas no
The CAS Registry Mumber 76330-71-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,3,3 and 0 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 76330-71:
(7*7)+(6*6)+(5*3)+(4*3)+(3*0)+(2*7)+(1*1)=127
127 % 10 = 7
So 76330-71-7 is a valid CAS Registry Number.
InChI:InChI=1/C22H22FN3O2S/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29)
76330-71-7Relevant articles and documents
Piperidinylalkyl quinazoline compounds, composition and method of use
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, (2008/06/13)
Novel quinazoline derivatives, comprising in the heterocyclic part of their quinazoline nucleus at least one carbonyl or thiocarbonyl group and a particularly substituted piperidinyl-alkyl side chain, said compounds being potent serotonin-antagonists.