76336-96-4

Basic information

• Product Name: Methanone, [(2R,3S)-3-(2-chlorophenyl)-2-aziridinyl]phenyl-, rel-
• CAS NO: 76336-96-4
• Molecular Formula: C15H12ClNO
• Molecular Weight: 257.719
• Mol File: 76336-96-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Methanone, [(2R,3S)-3-(2-chlorophenyl)-2-aziridinyl]phenyl-, rel-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, [(2R,3S)-3-(2-chlorophenyl)-2-aziridinyl]phenyl-, rel-(76336-96-4)
• EPA Substance Registry System: Methanone, [(2R,3S)-3-(2-chlorophenyl)-2-aziridinyl]phenyl-, rel-(76336-96-4)

Safety Data

• Hazardous Substances Data: 76336-96-4(Hazardous Substances Data)

Upstream product

• 22966-11-6 (2E)-3-(2-chlorophenyl)-1-phenylprop-2-en-1-one 
• 3300-67-2 3-(2-chlorophenyl)-1-phenylpropenone 

Downstream Products

• 22966-11-6 (2E)-3-(2-chlorophenyl)-1-phenylprop-2-en-1-one 

Relevant articles and documents

Efficient aziridination of α,β-unsaturated ketones with O-(2,4-dinitrophenyl)-hydroxylamine

The aziridination of α,β-unsaturated ketones with O-(2,4-dinitrophenyl)-hydroxylamine and tertiary amine was developed. trans-Aziridines were obtained exclusively in good yields. The reaction is proposed to occur via an aminimide intermediate. Copyright T

Facile preparation of allyl amines and pyrazoles by hydrazinolysis of 2-ketoaziridines

Allyl amines and pyrazoles can be obtained by hydrazinolysis of 2-ketoaziridines. A variety of aziridines, including N-unprotected, N-substituted, as well as bicyclic enamine and aminal type, can be transformed into diversely substituted linear or cyclic products. The hydrazinolysis of homochiral aziridines proceeds without racemization.

Direct NH-aziridination of α,β-unsaturated ketones

1-Aryl-α,β-unsaturated ketones were directly aziridinated, N-unsubstituted, in a one-pot reaction with satisfactory yields by N,N′-diamino-1,4-diazoniabicyclo[2.2.2]octane dinitrate, a nitrogen-nitrogen ylide precursor, in the presence of sodium hydride.