76360-42-4 Usage
General Description
Methyl 2-chlorothiophene-3-carboxylate is a chemical compound with the molecular formula C8H7ClO2S. It is a derivative of thiophene, which is a heterocyclic compound containing a sulfur atom in its five-membered ring. The presence of a chloro group and a carboxylate ester group in this compound makes it useful in organic synthesis and pharmaceutical industries. It is often employed as an intermediate in the production of various pharmaceuticals and agrochemicals due to its ability to participate in numerous chemical reactions. Methyl 2-chlorothiophene-3-carboxylate is a colorless to light yellow liquid with a distinctive odor, and it should be handled and stored carefully due to its potential hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 76360-42-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,3,6 and 0 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 76360-42:
(7*7)+(6*6)+(5*3)+(4*6)+(3*0)+(2*4)+(1*2)=134
134 % 10 = 4
So 76360-42-4 is a valid CAS Registry Number.
76360-42-4Relevant articles and documents
BISARYL HETEROCYCLES AS NRF2 ACTI
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Page/Page column 104; 106, (2018/07/05)
The present invention relates to bisaryl heterocycle compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators. In particular, the invention relates to bisaryl heterocycles of Formula (I),
Synthesis and antitumour activity of new derivatives of flavone-8- acetic acid (FAA). Part 31): 2-Heteroaryl derivatives
Aitken, R. Alan,Bibby, Michael C.,Bielefeldt, Florian,Double, John A.,Laws, Andrea L.,Mathieu, Anne-Laure,Ritchie, Robert B.,Wilson, David W. J.
, p. 405 - 411 (2007/10/03)
A range of 14 derivatives of flavone-8-acetic acid (FAA) with a heterocyclic substituent in place of the 2-phenyl group have been prepared and their anti-tumour activity evaluated in vitro against a panel of human and murine tumour cell lines and in vivo against MAC 15A. Some of the compounds, notably 2c,d and s, showed significant in vivo activity and these require further studies in order to evaluate their potential for development.
