76387-89-8

Basic information

• Product Name: 6-methyl-1-phenyl-4-(p-tolyl)pyrimidin-2(1H)-one
• CAS NO: 76387-89-8
• Molecular Weight: 276.338
• Mol File: 76387-89-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-methyl-1-phenyl-4-(p-tolyl)pyrimidin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-1-phenyl-4-(p-tolyl)pyrimidin-2(1H)-one(76387-89-8)
• EPA Substance Registry System: 6-methyl-1-phenyl-4-(p-tolyl)pyrimidin-2(1H)-one(76387-89-8)

Safety Data

• Hazardous Substances Data: 76387-89-8(Hazardous Substances Data)

Upstream product

• 4023-79-4 1-(4-methylphenyl)butan-1,3-dione 
• 64-10-8 phenyl carbamate 

Relevant articles and documents

The Selective Preparation of 1,4-Diaryl-6-methyl- and 1,6-Diaryl-4-methyl-2-(1H)pyrimidinones

N-Phenylurea reacted with benzoylacetone derivatives (I) to give 1,4-diaryl-6-methyl-2-(1H)pyrimidinones (II) in addition to low yields of 1,6-diaryl-4-methyl-2-(1H)pyrimidinones (IV), while N-phenylthiourea afforded only 1,6-diaryl-4-methyl-2-(1H)pyrimidinethiones (III) in good yields.Further 1,6-diaryl-4-methyl-2-(1H)pyrimidinethiones (III) were succesfully converted in satisfactory yields into the corresponding 2-(1H)pyrimidinones (IV) by the treatment with methyl iodide in the presence of sodium methoxide in methanol at room temperature.