76447-19-3

Basic information

• Product Name: 2-nitro-4-methyl-3,5-dimethoxybenzoic acid
• Synonyms: 2-nitro-4-methyl-3,5-dimethoxybenzoic acid
• CAS NO: 76447-19-3
• Molecular Weight: 241.2
• Mol File: 76447-19-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-nitro-4-methyl-3,5-dimethoxybenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-nitro-4-methyl-3,5-dimethoxybenzoic acid(76447-19-3)
• EPA Substance Registry System: 2-nitro-4-methyl-3,5-dimethoxybenzoic acid(76447-19-3)

Safety Data

• Hazardous Substances Data: 76447-19-3(Hazardous Substances Data)

Upstream product

• 61040-81-1 4-methyl-3,5-dimethoxybenzoic acid 
• 60441-79-4 methyl 3,5-dimethoxy-4-methylbenzoate 
• 76447-17-1 Methyl 4-Methyl-3,5-dimethoxy-2-nitrobenzoate 

Downstream Products

• 76447-26-2 Ethyl 1-(2-Nitro-4-methyl-3,5-dimethoxybenzoyl)-(E)-4-(1-propenyl)pyrrole-2-carboxylate 
• 76447-27-3 Ethyl 1-(2-Nitro-4-methyl-3,5-dimethoxy-benzoyl)-4-propylpyrrole-2-carboxylate 
• 76447-28-4 Ethyl 1-(2-Amino-4-methyl-3,5-dimethoxybenzoyl)-(E)-4-(1-propenyl)pyrrole-2-carboxylate 
• 76447-20-6 4-methyl-3,5-dimethoxy-2-nitro-benzoyl chloride 
• 71955-96-9 4-Methyl-3,5-dimethoxyanthranilic Acid 

Relevant articles and documents

Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex

The present invention relates to non-steroidal ligands for use in nuclear receptor-based inducible gene expression system, and a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene.

Pyrrolobenzodiazepines

Compounds of the formulae Ia and Ib: wherein:A is CH2, or a single bond;R2 is selected from: R, OH, OR, CO2H, CO2R, COH, COR, SO2R, CN;R6, R7 and R9 are independently selected from H, R, OH, OR, halo, amino, NHR, nitro, Me3Sn;and R8 is selected from H, R, OH, OR, halo, amino, NHR, nitro, Me3Sn, where R is as defined above, or the compound is a dimer with each monomer being the same or different and being of formula Ia or Ib, where the R8 groups of the monomers form together a bridge having the formula -X-R'-X- linking the monomers, where R' is an alkylene chain containing from 3 to 12 carbon atoms, which chain may be interrupted by one or more hetero-atoms and/or aromatic rings and may contain one or more carbon-carbon double or triple bonds, and each X is independently selected from O, S, or N; except that in a compound of formula Ia when A is a single bond, then R2 is not CH=CH(CONH2) or CH=CH(CONMe2). Other related compounds are also disclosed.