76462-17-4

Basic information

• Product Name: 2-Amino-3-Methylbenzenethiol
• Synonyms: 2-Amino-3-Methylbenzenethiol;2-Amino-3-methybenzenethiol, 95%
• CAS NO: 76462-17-4
• Molecular Formula: C₇H₉NS
• Molecular Weight: 139.21806
• Mol File: 76462-17-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 48 °C
• Boiling Point: 252.3±20.0 °C(Predicted)
• Appearance: /
• Density: 1.154±0.06 g/cm3(Predicted)
• PKA: 8.26±0.10(Predicted)
• CAS DataBase Reference: 2-Amino-3-Methylbenzenethiol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-3-Methylbenzenethiol(76462-17-4)
• EPA Substance Registry System: 2-Amino-3-Methylbenzenethiol(76462-17-4)

Safety Data

• Hazardous Substances Data: 76462-17-4(Hazardous Substances Data)

Usage

General Description

2-Amino-3-methylbenzenethiol, also known as 3-(methylthio)aniline, is a chemical compound with the molecular formula C7H9NS. It is a thiol compound and an important building block in organic synthesis for the production of pharmaceuticals and fine chemicals. The compound is used as a starting material for the synthesis of various pharmaceutical drugs, including antihypertensive agents and other medicinally active compounds. It is also used as a building block for the production of dyes, pigments, and other industrial chemicals. 2-Amino-3-methylbenzenethiol is a colorless to pale yellow liquid with a strong, unpleasant odor, and it should be handled and stored with proper safety precautions due to its potential toxicity and reactivity.

Upstream product

• 614-78-8 o-tolylthiourea 
• 636-21-5 o-toluidine hydrochloride 
• 53065-21-7 2-amino-4-methylbenzothiazole hydrobromide 
• 3048-48-4 4-methylbenzo[d]thiazole 

Downstream Products

• 79838-65-6 4-(2-Amino-3-methyl-phenylsulfanyl)-3-nitro-benzoic acid 
• 690243-03-9 2-(2-chloro-5-nitro-phenyl)-4-methyl-benzothiazole 
• 220328-24-5 benzyl 3,5-dimethyl-4H-1,4-benzothiazine-2-carboxylate 
• 3048-48-4 4-methylbenzo[d]thiazole 
• 93075-16-2 2-methyl-6-(2-nitro-phenylsulfanyl)-aniline 
• 126308-12-1 (2,4-Dimethoxy-phenyl)-(3,5-dimethyl-4H-benzo[1,4]thiazin-2-yl)-methanone 
• 121364-15-6 Biphenyl-4-yl-(3,5-dimethyl-4H-benzo[1,4]thiazin-2-yl)-methanone 
• 93075-17-3 2-(4-Bromo-2-nitro-phenylsulfanyl)-6-methyl-phenylamine 
• 93091-65-7 2-Methyl-6-(2-nitro-4-trifluoromethyl-phenylsulfanyl)-phenylamine 
• 79838-66-7 2-(2,4-Dinitro-phenylsulfanyl)-6-methyl-phenylamine 

Relevant articles and documents

Novel SIRT 1 activator and medical use thereof

The present invention relates to a SIRT 1 activator and medical uses thereof. In the present invention, a novel SIRT 1 activator compound based on a benzo[d]thiazole skeleton, a crystalline form thereof, a hydrate thereof or a salt thereof is prepared, and effect on alleviating obesity, insulin resistance and dyslipidemia, alleviating fatty liver, preventing cell aging, preventing oxidative stress and extending of life of yeast. Therefore, the novel SIRT 1 activator compound having the above effects can be used for a pharmaceutical composition for therapeutic use for preventing or treating metabolic diseases including obesity, diabetes mellitus, dyslipidemia and the like and liver diseases including alcoholic or non-alcoholic fatty liver, fatty liver diseases and the like, and a health food composition for alleviating cell aging or prolonging the life span, and the like.COPYRIGHT KIPO 2018

Synthesis and antioxidant activity of quinolinobenzothiazinones

A new series of structurally diverse quinolinobenzothiazinones has been synthesized with the annulation of heterocyclic structural pharmacophores. The synthesized quinolinobenzothiazinones have been evaluated for their antioxidant (LPO & GSH) and radical scavenging activities (DPPH and ABTS assays).