76463-86-0Relevant articles and documents
Synthesis and activity of 4,5-diarylimidazoles as human CB1 receptor inverse agonists
Plummer, Christopher W.,Finke, Paul E.,Mills, Sander G.,Wang, Junying,Tong, Xinchun,Doss, George A.,Fong, Tung M.,Lao, Julie Z.,Schaeffer, Marie-Therese,Chen, Jing,Shen, Chun-Pyn,Stribling, D. Sloan,Shearman, Lauren P.,Strack, Alison M.,Van Der Ploeg, Lex H.T.
, p. 1441 - 1446 (2007/10/03)
Structure-activity relationship studies directed toward the optimization of 4,5-diarylimidazole-2-carboxamide analogs as human CB1 receptor inverse agonists resulted in the discovery of the two amide derivatives 24a and b (hCB1 IC50 = 6.1 and 4
The Copper-Catalysed Reaction of 2-Chloroimidazoles and 2-Chlorobenzimidazoles with Dimethylamine
Whittle, Chrostopher P.
, p. 1545 - 1551 (2007/10/02)
The preparation of 2-dimethylamino-benzimidazoles and -imidazoles from the corresponding 2-chloro compounds by reaction with dimethylamine is assisted by the presence of copper salts.In the absence of a copper catalyst, 2-chloroimidazoles fail to react.Ki
