76527-29-2Relevant articles and documents
Electrolytic Oxidation of Ketones in a Methanolic Solution of NaCN in the Presence of Catalytic Amounts of KI
Okimoto, Mitsuhiro,Chiba, Toshiro
, p. 6194 - 6197 (2007/10/02)
The indirect electrolytic oxidation of ketones (1) in methanolic sodium cyanide was studied using iodide ion as a mediator.The product and the reactivity of ketone were dependent on the nature of the alkyl groups attached to the carbonyl group.Thus, 2-alk
SYNTHESIS OF α,β-EPOXY DIAZOMETHYL KETONES
Thijs, L.,Smeets, F. L. M.,Cillissen, P. J. M.,Harmsen, J.,Zwanenburg, B.
, p. 2141 - 2144 (2007/10/02)
The preparation of eighteen epoxy diazomethyl ketones 1 is described.Two general methods were developed.Firstly, treatment of the mixed anhydrides of glycidic acids and carbonic acid ester with diazomethane led to the title compounds in yields ranging from 17-74 percent.Secondly, glycidyl chlorides which were obtained from sodium glycidates and oxalyl chloride, gave the desired products upon treatment with diazomethane ( yields 60-74 percent).The required α,β-epoxy carboxylic esters were prepared by Darzens condensation and epoxidation of α,β-unsaturated esters, but in some cases also by reaction of α-oxo carboxylic esters with diazomethane.