76574-37-3 Usage
Description
4-Amino-6-chloro-2-methylpyrimidine-5-carbonitrile is a pyrimidine derivative with a molecular formula C6H5ClN4 and a molecular weight of 170.59 g/mol. It is a chemical compound that exhibits various biological activities and has potential applications in the treatment of certain diseases.
Uses
Used in Pharmaceutical Research and Development:
4-Amino-6-chloro-2-methylpyrimidine-5-carbonitrile is used as a key intermediate in the synthesis of various drugs, including antimalarial and antiviral agents. Its unique structure and properties make it a valuable building block for the development of new therapeutic agents.
Used in Agrochemicals:
This chemical compound is also utilized in the field of agrochemicals, where it serves as an important building block in the synthesis of other organic compounds. Its versatility and reactivity contribute to the development of effective agrochemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 76574-37-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,5,7 and 4 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 76574-37:
(7*7)+(6*6)+(5*5)+(4*7)+(3*4)+(2*3)+(1*7)=163
163 % 10 = 3
So 76574-37-3 is a valid CAS Registry Number.
76574-37-3Relevant articles and documents
Antihypertensive Activity of 6-Arylpyridopyrimidin-7-amine Derivatives
Bennett, Lawrence R.,Blankley, C. John,Fleming, Robert W.,Smith, Ronald D.,Tessman, Deirdre K.
, p. 382 - 389 (2007/10/02)
A series of 51 6-arylpyridopyrimidin-7-amine derivatives was prepared and evaluated for antihypertensive activity in the conscious spontaneously hypertensive rat.A number of these compounds, notably 6-(2,6-dichlorophenyl)-2-methylpyridopyrimidin-7-amine (36), lowered blood pressure in these rats in a gradual and sustained manner to normotensive levels at oral doses of 10-50 mg/kg.Normalized blood pressure levels could then be maintained by single daily oral doses.The effect of structural variation in the 6-aryl group and in the 2 and 4 positions of the pyridopyrimidine ring on activity is reported and discussed.
