76631-46-4

Basic information

• Product Name: 4-(2,3-DIMETHYL-BENZYL)-1H-IMIDAZOLE
• Synonyms: 4-(2,3-DIMETHYL-BENZYL)-1H-IMIDAZOLE;detomidine;1H-Imidazole, 4-((2,3-dimethylphenyl)methyl)-;4-(2,3-Dimethylbenzyl)imidazol;90038-01-0 (Monohydrochloride);Detomidina;Detomidina [inn-spanish];Detomidine [inn:ban]
• CAS NO: 76631-46-4
• Molecular Formula: C12H14N2
• Molecular Weight: 186.25296
• Mol File: 76631-46-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 114-116°
• Boiling Point: 386.5 °C at 760 mmHg
• Flash Point: 200.6 °C
• Appearance: /
• Density: 1.077 g/cm³
• Vapor Pressure: 7.83E-06mmHg at 25°C
• Refractive Index: 1.582
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 14.44±0.10(Predicted)
• CAS DataBase Reference: 4-(2,3-DIMETHYL-BENZYL)-1H-IMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2,3-DIMETHYL-BENZYL)-1H-IMIDAZOLE(76631-46-4)
• EPA Substance Registry System: 4-(2,3-DIMETHYL-BENZYL)-1H-IMIDAZOLE(76631-46-4)

Safety Data

• Hazardous Substances Data: 76631-46-4(Hazardous Substances Data)

Usage

Description

4-(2,3-DIMETHYL-BENZYL)-1H-IMIDAZOLE is an organic compound with the molecular formula C14H14N2. It is characterized by its imidazole ring structure, which is fused with a benzene ring, and a dimethyl-substituted benzyl group attached to the imidazole. 4-(2,3-DIMETHYL-BENZYL)-1H-IMIDAZOLE is known for its potential applications in various industries due to its unique chemical properties.

Uses

Used in Pharmaceutical Industry:
4-(2,3-DIMETHYL-BENZYL)-1H-IMIDAZOLE is used as an active pharmaceutical ingredient for its analgesic and sedative-hypnotic properties. It is particularly effective as a veterinary analgesic, providing pain relief to animals. Additionally, its sedative-hypnotic activity makes it a valuable compound for inducing calmness and promoting sleep in both humans and animals.
Used in Veterinary Medicine:
In the veterinary field, 4-(2,3-DIMETHYL-BENZYL)-1H-IMIDAZOLE is used as an analgesic to alleviate pain in animals. Its effectiveness in pain management makes it a valuable asset in veterinary medicine, where it can be used to treat various conditions that cause discomfort or pain in animals.
Used in Sedative and Hypnotic Formulations:
4-(2,3-DIMETHYL-BENZYL)-1H-IMIDAZOLE is also used as a sedative and hypnotic agent. Its calming effects make it suitable for use in formulations designed to promote relaxation and sleep, particularly in cases where anxiety or stress may be contributing factors.
Used in α-Adrenoceptor Agonist Applications:
As a α-Adrenoceptor agonist, 4-(2,3-DIMETHYL-BENZYL)-1H-IMIDAZOLE exhibits sedative and analgesic activity. This property makes it useful in the development of medications that target the α-adrenergic receptors, which play a crucial role in the regulation of various physiological processes, including blood pressure, pupil dilation, and sedation.

InChI:InChI=1/C12H14N2/c1-9-4-3-5-11(10(9)2)6-12-7-13-8-14-12/h3-5,7-8H,6H2,1-2H3,(H,13,14)

Upstream product

• 791644-56-9 C₁₁H₁₂N₄O₂S 
• 183158-34-1 2,3-dimethylphenylboronic acid 

Relevant articles and documents

Application of Barluenga Boronic Coupling (BBC) to the Parallel Synthesis of Drug-like and Drug Fragment-like Molecules

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