766515-35-9 Usage
General Description
5-IODO-1-METHYL-1H-PYRAZOLO[3,4-B] PYRIDIN-3-AMINE is a chemical compound with the molecular formula C6H6IN5. It is a pyrazolopyridinamine, part of the pyrazole class of compounds known for their nitrogen-rich heterocyclic ring structure. Its key structural aspects include several nitrogen atoms and an iodine substituent. It is primarily used in scientific research, particularly in the development and testing of various pharmaceuticals. Its exact properties, including toxicity, reactivity, and biological activity, are dependent on the specific experimental or research context in which it is used.
Check Digit Verification of cas no
The CAS Registry Mumber 766515-35-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,6,5,1 and 5 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 766515-35:
(8*7)+(7*6)+(6*6)+(5*5)+(4*1)+(3*5)+(2*3)+(1*5)=189
189 % 10 = 9
So 766515-35-9 is a valid CAS Registry Number.
766515-35-9Relevant articles and documents
Synthesis of 3,5-difunctionalized 1-methyl-1H-pyrazolo[3,4-b]pyridines involving palladium-mediated coupling reactions
Lavecchia,Berteina-Raboin,Guillaumet
, p. 6633 - 6636 (2004)
Indirect iodination of 2-chloro-nicotinonitrile gave 2-chloro-5- iodonicotinonitrile, which was cyclized with methylhydrazine to lead to 3-amino-5-iodopyrazolo[3,4-b]pyridine. Position 3 was then protected by pivaloyl group and the resulting 5-iodo-3-pivaloylaminopyrazolo[3,4-b]pyridine was engaged in palladium-promoted coupling reactions with various reagents to give 3-pivaloylamino-5-substituted compounds. Deprotection and iododediazoniation followed by cross-coupling reactions in position 3 afforded novel unsymmetrical 3,5-disubstituted pyrazolo[3,4-b]pyridine species.