7666-04-8 Usage
Description
2-(Methylthio)imidazole is an organic compound characterized by the presence of a methylthio group attached to the imidazole ring. It is known for its unique chemical properties and reactivity, making it a valuable intermediate in various chemical reactions and synthesis processes.
Uses
Used in Pharmaceutical Industry:
2-(Methylthio)imidazole is used as a reagent for the synthesis of 4-Methyl-5-phenyl-(1,2,4)-triazoles, which are selective inhibitors of 11β-hydroxysteroid dehydrogenase type I (11β-HSD1). This enzyme plays a crucial role in the regulation of glucocorticoid hormones, and its inhibition can have therapeutic benefits in treating various metabolic and inflammatory disorders. The use of 2-(Methylthio)imidazole in the synthesis of these triazoles contributes to the development of potential drug candidates for such applications.
Check Digit Verification of cas no
The CAS Registry Mumber 7666-04-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,6 and 6 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 7666-04:
(6*7)+(5*6)+(4*6)+(3*6)+(2*0)+(1*4)=118
118 % 10 = 8
So 7666-04-8 is a valid CAS Registry Number.
InChI:InChI=1/C4H6N2S/c1-7-4-5-2-3-6-4/h2-3H,1H3,(H,5,6)
7666-04-8Relevant articles and documents
SUBSTITUTED IMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS
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Paragraph 00543, (2021/04/01)
The invention provides substituted imidazole carboxamides and related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat a medical disorder, e.g., cancer, lysosomal storage disorder, neurodegenerative disorder, inflammatory disorder, in a patient.
5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE COMPOUNDS
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Page/Page column 22, (2011/05/08)
The invention relates to 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine derivatives of formula (I) wherein R1, R2, R3, and R4 are as described n the description, to salts, especially pharmaceutically acceptable salts thereof, and to the use of such compounds as medicaments; especially as orexin receptor antagonists.
5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE COMPOUNDS
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Page/Page column 49, (2010/01/30)
The invention relates to 5,6,7,8-tetrahydro-imidazo[1,5- a]pyrazine derivatives of formula (I) wherein R1, R2, R3, and R4 are as described n the description, to salts, especially pharmaceutically acceptable salts thereof, and to the use of such compounds as medicaments; especially as orexin receptor antagonists.