76711-49-4

Basic information

• Product Name: 4-(tert-Butyldimethylsilyloxy)-3-methylcyclohex-2-en-1-one
• Synonyms: 4-(tert-Butyldimethylsilyloxy)-3-methylcyclohex-2-en-1-one
• CAS NO: 76711-49-4
• Molecular Weight: 240.418
• Mol File: 76711-49-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(tert-Butyldimethylsilyloxy)-3-methylcyclohex-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(tert-Butyldimethylsilyloxy)-3-methylcyclohex-2-en-1-one(76711-49-4)
• EPA Substance Registry System: 4-(tert-Butyldimethylsilyloxy)-3-methylcyclohex-2-en-1-one(76711-49-4)

Safety Data

• Hazardous Substances Data: 76711-49-4(Hazardous Substances Data)

Upstream product

• 13697-84-2 1-methoxy-5-methyl-cyclohexa-1,4-diene 
• 31883-98-4 3-methylcyclohex-3-en-1-one 
• 184481-10-5 1-methyl-7-oxabicyclo<4.1.0>heptan-3-one 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 57356-79-3 4-hydroxy-3-methyl-cyclohex-2-en-1-one 

Relevant articles and documents

A stereocontrolled approach towards highly oxygenated taxane C and CD-ring precursors

Based upon a remarkable β-face diastereoselection, a stereocontrolled construction of bicyclic systems with the appropriate stereochemical disposition of the substituents belonging either to a Baccatin-I C-ring precursor or a Taxol CD-ring precursor is reported.

Synthetic studies on the ambiguine family of alkaloids: Construction of the ABCD ring system

A racemic synthesis of the ABCD ring core of the ambiguines that preserves the tertiary alcohol has been accomplished in a convergent synthesis in 10 synthetic steps, in an overall yield of 46% from commercially available 4-bromoindole and m-methylanisole