76872-75-8

Basic information

• Product Name: 5-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
• Synonyms: 5-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
• CAS NO: 76872-75-8
• Molecular Weight: 244.274
• Mol File: 76872-75-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 5-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione(76872-75-8)
• EPA Substance Registry System: 5-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione(76872-75-8)

Safety Data

• Hazardous Substances Data: 76872-75-8(Hazardous Substances Data)

Upstream product

• 4815-36-5 ethyl 2-amino-4-phenyl-thiophene-3-carboxylate 
• 151-50-8 potassium cyanide 
• 98-86-2 acetophenone 
• 17277-47-3 (Z)-2-cyano-3-phenylbut-2-enoic acid ethyl ester 
• 67171-55-5 2-amino-4-phenylthiophene-3-carboxylic acid methyl ester 
• 57-13-6 urea 

Downstream Products

• 76872-27-0 2,4-dichloro-5-phenyl-thieno[2,3-d]pyrimidine 
• 1401985-61-2 (S)-1-{5-phenyl-4-[(pyridin-2-ylmethyl)amino]thieno[2,3-d]pyrimidin-2-yl}piperidine-3-carboxylic acid 
• 1401985-49-6 N-(2-hydroxyethyl)-1-{5-phenyl-4-[(pyridin-2-ylmethyl)amino]thieno[2,3-d]pyrimidin-2-yl}piperidine-3-carboxamide 
• 108311-88-2 (2,4-Dioxo-5-phenyl-1,4-dihydro-2H-thieno[2,3-d]pyrimidin-3-yl)-acetic acid ethyl ester 
• 1401985-56-5 (3S)-N-(2-hydroxyethyl)-1-{5-phenyl-4-[(pyridin-2-ylmethyl)amino]thieno[2,3-d]pyrimidin-2-yl}piperidine-3-carboxamide 
• 64572-05-0 3-methyl-5-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-dione 
• 76872-51-0 2-Chloro-5-phenyl-3,4-dihydro-thieno[2,3-d]pyrimidine 

Relevant articles and documents

ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) MODULATORS AND USES THEREOF

Provided herein are small molecule modulators of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds.

Heteroarylpyrimindinedione derivative and use thereof

The invention provides a heteroarylpyrimindinedione derivative and use thereof. The heteroarylpyrimindinedione derivative comprises a compound with a structure shown as general formula I, and a pharmaceutically acceptable salt or hydrate thereof. The derivative is obtained by chemical synthesis, and pharmacological experiments prove that the active ligand with cannabinoid type II receptor CB2 can be used for preparation of drugs for prevention and mitigation of CB2 receptor-mediated diseases, and the drug is cannabinoid CB2 receptor agonist's agonist, partial agonist, inverse agonist or antagonist. And the general structural formula I is shown as the specification.

THIENO [2, 3 -D] PYRIMIDINE DERIVATIVES AND THEIR USE TO TREAT ARRHYTHMIA

The present invention relates to thienopyrimidine compounds which are potassium channel inhibitors. Pharmaceutical compositions comprising the compounds and their use in the treatment of arrhythmia are also described.