76960-00-4

Basic information

• Product Name: 4-hydroxy-1,4-bis(4-methoxyphenyl)butan-1-one
• Synonyms: 4-hydroxy-1,4-bis(4-methoxyphenyl)butan-1-one
• CAS NO: 76960-00-4
• Molecular Weight: 300.354
• Mol File: 76960-00-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-hydroxy-1,4-bis(4-methoxyphenyl)butan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydroxy-1,4-bis(4-methoxyphenyl)butan-1-one(76960-00-4)
• EPA Substance Registry System: 4-hydroxy-1,4-bis(4-methoxyphenyl)butan-1-one(76960-00-4)

Safety Data

• Hazardous Substances Data: 76960-00-4(Hazardous Substances Data)

Upstream product

• 1191-99-7 2,3-dihydro-2H-furan 
• 696-62-8 para-iodoanisole 
• 637-69-4 4-Methoxystyrene 
• 58518-78-8 p-methoxyphenacyl acetate 
• 50990-31-3 (4-methoxyphenyl)(2-(4-methoxyphenyl)cyclopropyl)methanone 

Relevant articles and documents

Preparation of aromatic γ-hydroxyketones by means of Heck coupling of aryl halides and 2,3-dihydrofuran, catalyzed by a palladium(ii) glycine complex under microwave irradiation

A series of aromatic γ-hydroxyketones were prepared by means of Heck coupling reaction of aryl halides and 2,3-dihydrofuran, catalyzed by PdCl2·Gly2 and under microwave irradiation. This synthetic transformation involves the formation of an aryl-dihydrofuranoic intermediate, followed by an unusual opening of the heterocycle promoted by a water molecule and the formation of the ketone carbonyl function through keto-enol tautomerism. This journal is

TRAPPING THE INTERMEDIATE INVOLVED IN THE INTRAMOLECULAR CYCLISATION OF CYCLOPROPYL KETONES. A CONVENIENT PREPARATION OF OPEN-CHAIN γ-HYDROXY KETONES.

The concerted mechanism for the stannic chloride catalysed cyclisation of aryl cyclopropyl ketones is disproved by trapping the intermediate.The reaction provides a facile route to γ-hydroxyketones.