77-02-1 Usage
Description
APROBARBITAL METHANOL SOLUTION is a member of the barbiturate class, characterized by a pyrimidine-2,4,6(1H,3H,5H)-trione structure substituted with an isopropyl and a prop-1-en-3-yl group at position 5. It is a pharmaceutical compound with sedative and hypnotic properties, commonly used in medical and research applications.
Uses
Used in Pharmaceutical Industry:
APROBARBITAL METHANOL SOLUTION is used as a sedative and hypnotic agent for inducing sleep and treating insomnia. Its barbiturate nature allows it to depress the central nervous system, providing a calming effect and promoting restful sleep.
Used in Research Applications:
In the field of scientific research, APROBARBITAL METHANOL SOLUTION is utilized for studying the effects of barbiturates on the central nervous system and their potential applications in various medical conditions. This includes investigating its role in anesthesia, seizure management, and other neurological disorders.
Please note that the provided materials do not mention any specific uses for APROBARBITAL METHANOL SOLUTION. The uses listed above are general applications of barbiturates in the pharmaceutical and research industries.
Originator
Alurate,Roche
Manufacturing Process
170 parts of isopropylbarbituric acid are mixed with 500 parts of water and
dissolved by adding 135 parts of a 30 percent of the solution of sodium
hydroxide. To this solution are added 130 parts of 130 parts of allylbromide.
An emulsion obtained is stirred at an inner temperature of about 25°C. The
reaction is at first accompanied by a slight development of heat. After 12
hours the reaction is brought to a close. When cooled down the
isopropylallylbarbituric acid is drawn off. The yield is more than 80 percent of
the theoretically calculated quantity. By crystallization from diluted alcohol the
pure isopropylallylbarbituric acid is obtained in colorless crystals of the melting
point 137-138°C.
Therapeutic Function
Sedative, Hypnotic
World Health Organization (WHO)
Aprobarbital is an intermediate-acting barbiturate. See WHO
comment for barbiturates.
Check Digit Verification of cas no
The CAS Registry Mumber 77-02-1 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 7 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 77-02:
(4*7)+(3*7)+(2*0)+(1*2)=51
51 % 10 = 1
So 77-02-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2O3/c1-4-5-10(6(2)3)7(13)11-9(15)12-8(10)14/h4,6H,1,5H2,2-3H3,(H2,11,12,13,14,15)