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77-02-1

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77-02-1 Usage

Description

APROBARBITAL METHANOL SOLUTION is a member of the barbiturate class, characterized by a pyrimidine-2,4,6(1H,3H,5H)-trione structure substituted with an isopropyl and a prop-1-en-3-yl group at position 5. It is a pharmaceutical compound with sedative and hypnotic properties, commonly used in medical and research applications.

Uses

Used in Pharmaceutical Industry:
APROBARBITAL METHANOL SOLUTION is used as a sedative and hypnotic agent for inducing sleep and treating insomnia. Its barbiturate nature allows it to depress the central nervous system, providing a calming effect and promoting restful sleep.
Used in Research Applications:
In the field of scientific research, APROBARBITAL METHANOL SOLUTION is utilized for studying the effects of barbiturates on the central nervous system and their potential applications in various medical conditions. This includes investigating its role in anesthesia, seizure management, and other neurological disorders.
Please note that the provided materials do not mention any specific uses for APROBARBITAL METHANOL SOLUTION. The uses listed above are general applications of barbiturates in the pharmaceutical and research industries.

Originator

Alurate,Roche

Manufacturing Process

170 parts of isopropylbarbituric acid are mixed with 500 parts of water and dissolved by adding 135 parts of a 30 percent of the solution of sodium hydroxide. To this solution are added 130 parts of 130 parts of allylbromide. An emulsion obtained is stirred at an inner temperature of about 25°C. The reaction is at first accompanied by a slight development of heat. After 12 hours the reaction is brought to a close. When cooled down the isopropylallylbarbituric acid is drawn off. The yield is more than 80 percent of the theoretically calculated quantity. By crystallization from diluted alcohol the pure isopropylallylbarbituric acid is obtained in colorless crystals of the melting point 137-138°C.

Therapeutic Function

Sedative, Hypnotic

World Health Organization (WHO)

Aprobarbital is an intermediate-acting barbiturate. See WHO comment for barbiturates.

Check Digit Verification of cas no

The CAS Registry Mumber 77-02-1 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 7 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 77-02:
(4*7)+(3*7)+(2*0)+(1*2)=51
51 % 10 = 1
So 77-02-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2O3/c1-4-5-10(6(2)3)7(13)11-9(15)12-8(10)14/h4,6H,1,5H2,2-3H3,(H2,11,12,13,14,15)

77-02-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name aprobarbital

1.2 Other means of identification

Product number -
Other names 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylethyl)-5-(2-propenyl)-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:77-02-1 SDS