77001-50-4

Basic information

• Product Name: 4'-AMINO-5'-NITROBENZO-15-CROWN-5
• Synonyms: 4'-AMINO-5'-NITROBENZO-15-CROWN-5;4'-Amino-5'-nitrobenzo-15-crown-5 97%
• CAS NO: 77001-50-4
• Molecular Formula: C₁₄H₂₀N₂O₇
• Molecular Weight: 328.32
• Product Categories: Chelation/Complexation Compounds;Crown Ethers;Synthetic Reagents
• Mol File: 77001-50-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 148-151 °C(lit.)
• Boiling Point: 528°C at 760 mmHg
• Flash Point: 273.2°C
• Appearance: /
• Density: 1.237g/cm³
• Vapor Pressure: 3.08E-11mmHg at 25°C
• Refractive Index: 1.517
• CAS DataBase Reference: 4'-AMINO-5'-NITROBENZO-15-CROWN-5(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-AMINO-5'-NITROBENZO-15-CROWN-5(77001-50-4)
• EPA Substance Registry System: 4'-AMINO-5'-NITROBENZO-15-CROWN-5(77001-50-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• F: 9
• Hazardous Substances Data: 77001-50-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H20N2O7/c15-11-9-13-14(10-12(11)16(17)18)23-8-6-21-4-2-19-1-3-20-5-7-22-13/h9-10H,1-8,15H2

Upstream product

• 60835-71-4 4'-aminobenzo-15-crown-5-ether 
• 77001-48-0 N-(2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclopentadecin-15-yl)-acetamide 
• 14098-44-3 2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclopentadecin 
• 60835-69-0 4'-nitrobenzo-15-crown-5 
• 77001-49-1 15-(Acetylamino)-16-nitrobenzo<15>krone-5 

Downstream Products

• 83935-64-2 2-Isocyanato-3-nitro-6,7,9,10,12,13,15,16-octahydro-5,8,11,14,17-pentaoxa-benzocyclopentadecene 
• 83935-77-7 (3-Nitro-6,7,9,10,12,13,15,16-octahydro-5,8,11,14,17-pentaoxa-benzocyclopentadecen-2-yl)-carbamic acid methyl ester 
• 83935-66-4 1-(3,3-Diphenyl-propyl)-3-(3-nitro-6,7,9,10,12,13,15,16-octahydro-5,8,11,14,17-pentaoxa-benzocyclopentadecen-2-yl)-urea 
• 83935-69-7 1-[2-(3,4-Dimethoxy-phenyl)-ethyl]-3-(3-nitro-6,7,9,10,12,13,15,16-octahydro-5,8,11,14,17-pentaoxa-benzocyclopentadecen-2-yl)-urea 
• 99624-14-3 (3-Nitro-6,7,9,10,12,13,15,16-octahydro-5,8,11,14,17-pentaoxa-benzocyclopentadecen-2-yl)-carbamic acid 2-[2-(2-hydroxy-ethoxy)-phenoxy]-ethyl ester 
• 1334477-83-6 C₂₅H₂₆N₂O₅S 

Relevant articles and documents

Benzocrown Derivatives as Ionophores for Alkali Cations, I. - Synthesis of Urethane- and Urea-Linked Mono- and Bis-Crown Ethers

New mono- and bis-benzocrown ethers (5-28 and 29-48) with different substituents and connecting chains were prepared with the aim to develop novel alkali cation-transport mediators for biological systems.The alkali cation selectivities of the title compounds were determined in ion-selective membrane electrodes.Remarkable potassium selectivity was observed with several bis(benzo-15-crown-5)urethanes.

Double Ionophore with Dihydrotetraazaannulene- and Crownether-Function

Benzocrown-5 (1) was converted in four steps into the 4-amino-5-nitro-derivative 5, which, after reduction to the diamine 6, cyclocondenses with 3-ethoxy-2-isopropylacrolein.The resulting trimacrocyclic ligand 7 chelates nickel(II) and cobalt(II) ions and, additionally, potassium and sodium ions, thus being a double ionophore.