77006-29-2 Usage
General Description
The chemical 2-AMINO-3-(3-HYDROXY-4-METHYL-ISOXAZOL-5-YL)-PROPIONIC ACID, also known as AMPA, is a potent agonist for the AMPA receptors in the central nervous system. It is an analog of glutamic acid and plays a key role in excitatory neurotransmission. AMPA is involved in the regulation of synaptic plasticity, learning, and memory. It has also been implicated in neurological disorders such as epilepsy and stroke. Due to its central role in the nervous system, AMPA and its analogs have been studied as potential therapeutic targets for various neurological conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 77006-29-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,0,0 and 6 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 77006-29:
(7*7)+(6*7)+(5*0)+(4*0)+(3*6)+(2*2)+(1*9)=122
122 % 10 = 2
So 77006-29-2 is a valid CAS Registry Number.
77006-29-2Relevant articles and documents
Nitrile Oxide Cycloaddition of Non-activated Alkynes: A Novel Approach to the Synthesis of Neuroactive Isoxazoles
Pevarello, Paolo,Amici, Raffaella,Colombo, Maristella,Varasi, Mario
, p. 2151 - 2152 (2007/10/02)
A general method for the unprecedented 1,3-dipolar cycloaddition of bromonitrile oxide to distributed non-activated alkynes provides a useful alternative route to the neuropharmacological tools AMPA and 4-methylhomoibotenic acid.
