772-03-2

Basic information

• Product Name: 2-VINYLQUINOLINE
• Synonyms: 2-Ethenylquinoline;2-Vinylquinoline, stabilized,99%;NSC 99356;2-VINYLQUINOLINE;2-ethenyl-quinolin;2-Vinylquinoline (stabilised);2-Vinylquinoline 97%
• CAS NO: 772-03-2
• Molecular Formula: C₁₁H₉N
• Molecular Weight: 155.2
• EINECS: 212-246-8
• Product Categories: monomer;Fused Ring Systems
• Mol File: 772-03-2.mol
• Article Data: 23

Chemical Properties

• Melting Point: 284-285 °C
• Boiling Point: 269.01°C (rough estimate)
• Flash Point: 111.9 °C
• Appearance: dark orange-brown liquid
• Density: 1.0300
• Vapor Pressure: 0.0117mmHg at 25°C
• Refractive Index: 1.6210 (estimate)
• Storage Temp.: 2-8°C
• PKA: 4.88±0.40(Predicted)
• CAS DataBase Reference: 2-VINYLQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-VINYLQUINOLINE(772-03-2)
• EPA Substance Registry System: 2-VINYLQUINOLINE(772-03-2)

Safety Data

• Hazardous Substances Data: 772-03-2(Hazardous Substances Data)

Usage

Chemical Properties

dark orange-brown liquid

InChI:InChI=1/C11H9N/c1-2-10-8-7-9-5-3-4-6-11(9)12-10/h2-8H,1H2

Upstream product

• 63487-23-0 β-N,N-dimethylaminoethylquinaldine 
• 91-22-5 quinoline 
• 1826-67-1 vinyl magnesium bromide 
• 1613-37-2 Quinoline N-oxide 
• 2005-43-8 2-bromoquinoline 
• 75927-49-0 pinacol vinylboronate 
• 91-63-4 2-methylquinoline 
• 50-00-0 formaldehyd 
• 123-91-1 1,4-dioxane 
• 4363-34-2 vinylboronic acid 
• 612-62-4 2-Chloroquinoline 
• 5470-96-2 quinoline 2-carbaldehyde 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 7486-35-3 tri-n-butyl(vinyl)tin 

Downstream Products

• 57961-97-4 2-[2-(4-methyl-piperazin-1-yl)-ethyl]-quinoline 
• 1375070-75-9 1,2-diphenyl-3-(quinolin-2-yl)butan-2-ol 
• 1375070-42-0 (2S,3R)-1,2-diphenyl-3-(quinolin-2-yl)butan-2-ol 
• 1613-34-9 2-ethylquinoline 
• 1375070-41-9 (2S,3R)-2-phenyl-3-(quinolin-2-yl)butan-2-ol 
• 1375070-68-0 C₁₉H₁₉NO 
• 1375070-70-4 C₁₉H₁₉NO 
• 1375070-69-1 C₁₉H₁₉NO 
• 1375070-74-8 2-phenyl-3-(quinolin-2-yl)butan-2-ol 
• 1417190-39-6 2-Bromo-6-fluoro-N-hydroxy-N-(2-quinolin-2-yl-ethyl)-benzamide 
• 77669-23-9 (E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)quinoline 

Relevant articles and documents

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Water-Sculpting of a Heterogeneous Nanoparticle Precatalyst for Mizoroki-Heck Couplings under Aqueous Micellar Catalysis Conditions

Powdery, spherical nanoparticles (NPs) containing ppm levels of palladium ligated by t-Bu3P, derived from FeCl3, upon simple exposure to water undergo a remarkable alteration in their morphology leading to nanorods that catalyze Mizoroki-Heck (MH) couplings. Such NP alteration is general, shown to occur with three unrelated phosphine ligand-containing NPs. Each catalyst has been studied using X-ray photoelectron spectroscopy (XPS), energy-dispersive X-ray spectroscopy (EDX), transmission electron microscopy (TEM), and cryogenic transmission electron microscopy (cryo-TEM) analyses. Couplings that rely specifically on NPs containing t-Bu3P-ligated Pd occur under aqueous micellar catalysis conditions between room temperature and 45 °C, and show broad substrate scope. Other key features associated with this new technology include low residual Pd in the product, recycling of the aqueous reaction medium, and an associated low E Factor. Synthesis of the precursor to galipinine, a member of the Hancock family of alkaloids, is suggestive of potential industrial applications.

SULFONYL-SUBSTITUTED BICYCLIC COMPOUND WHICH ACTS AS ROR INHIBITOR

Provided is a sulfonyl-substituted bicyclic compound (A) which acts as a RORγ inhibitor, said compound has good RORγ inhibitory activity and is expected to be used for treating diseases mediated by a RORγ receptor in mammals.

Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines

Cu-catalyzed three-component couplings of vinylazaarenes, B2(pin)2, and N-Boc imines are described. Oxidation of the initially formed boronate gives azaarene-containing, Boc-protected amino alcohols with reasonable to good diastereoselectivities.