77278-40-1

Basic information

• Product Name: tert-butyl 4-(benzoyloxy)piperazine-1-carboxylate
• Synonyms: tert-butyl 4-(benzoyloxy)piperazine-1-carboxylate
• CAS NO: 77278-40-1
• Molecular Weight: 306.362
• Mol File: 77278-40-1.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-(benzoyloxy)piperazine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(benzoyloxy)piperazine-1-carboxylate(77278-40-1)
• EPA Substance Registry System: tert-butyl 4-(benzoyloxy)piperazine-1-carboxylate(77278-40-1)

Safety Data

• Hazardous Substances Data: 77278-40-1(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 94-36-0 dibenzoyl peroxide 

Downstream Products

• 1220972-23-5 tert-butyl 4-(4-octylphenyl)piperazine-1-carboxylate 
• 1627118-70-0 tert-butyl-4-(2,3,5,6-tetrafluorophenyl)piperazine-1-carboxylate 
• 1618666-68-4 tert-butyl 4-(3-methyl-2-(1-phenylvinyl)phenyl)piperazine-1-carboxylate 
• 180576-04-9 tert-butyl 4-(2-(tert-butoxy)-2-oxoethyl)piperazine-1-carboxylate 
• 1510821-68-7 tert-butyl 4-(2-(3-methyl-5-oxo-2,5-dihydro-1H-pyrazol-1-yl)phenyl)piperazine-1-carboxylate 
• 1372404-90-4 tert-butyl 4-(4-phenylbutyl)piperazine-1-carboxylate 
• 352437-09-3 tert-butyl 4-(4-bromophenyl)piperazine-1-carboxylate 
• 1300857-32-2 tert-butyl 4-(5-(tert-butyl)-2-((2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)carbamoyl)phenyl)piperazine-1-carboxylate 

Relevant articles and documents

Copper-Catalyzed Aminoarylation of Alkenes via Aminyl Radical Addition and Aryl Migration

We describe a new strategy for aminoarylation of alkenes by copper-catalyzed smiles rearrangement using O-benzoylhydroxylamines as the amine reagent. This method affords various β-amino amide derivatives possessing a quaternary carbon center with wide functional group tolerance and high regioselectivity. The mechanistic studies indicate that the transformation can involve aminyl radical intermediates under acid-free condition.

Acid-Promoted Expeditious Syntheses of Aminated Dibenzosultams via Palladium/Norbornene Cooperatively Catalysed C?H Amination/Arylation

Herein we reported a protocol to access aminated benzofused sultams through sequential ortho-amination, followed by ipso-arylation of aryl iodide bearing sulfonamide functional group via palladium/norbornene coorperative catalysis. This reaction has showcased a broad spectrum of substrate scope under mild conditions with moderate to good efficiency. (Figure presented.).

A carboxylate-assisted amination/unactivated C(sp2)-H arylation reactionviaa palladium/norbornene cooperative catalysis

This report describes a carboxylate-assisted palladium-catalysed Catellani reaction, which is compatible withortho-amination and unactivated C(sp2)-H arylation. This method was used to synthesize a series of 1-amino substituted dihydrophenanthridines, phenanthridines and 6H-benzo[c]chromenes. Based on kinetic isotope experiments, the kinetic curve proves that pivalic acid accelerates the reaction rate of unactivated C(sp2)-H activation, and thus this rate can keep up with the five membered aryl-norbornene-palladacycle (ANP) intermediate.