7732-97-0 Usage
Description
Estra-1,3,5(10)-triene-3,17beta-diol diheptanoate, also known as Estradiol Dienanthate, is a synthetic esterified form of estradiol, the primary estrogen hormone secreted by the premenopausal ovary. It is a metabolite of estradiol and has a chemical structure characterized by the presence of three double bonds and a 17-beta-hydroxyl group. The diheptanoate esterification allows for controlled release and extended duration of action compared to the native hormone.
Uses
Used in Pharmaceutical Industry:
Estra-1,3,5(10)-triene-3,17beta-diol diheptanoate is used as a pharmaceutical agent for hormone replacement therapy (HRT) in postmenopausal women. It helps alleviate symptoms associated with menopause, such as hot flashes, night sweats, and vaginal dryness, by providing the body with the necessary estrogen levels.
Additionally, it is used as a contraceptive agent in combination with progestogens to prevent ovulation and thus, pregnancy. The controlled release of estradiol from its diheptanoate ester allows for a more stable hormone level, ensuring effective contraception.
Used in Fertility Treatments:
In the field of fertility treatments, Estra-1,3,5(10)-triene-3,17beta-diol diheptanoate is utilized to support the development of ovarian follicles and improve the chances of successful conception. Its controlled release mechanism ensures a steady supply of estradiol, which is crucial for the maturation of eggs and the overall reproductive process.
Used in Hormone Therapy for Transgender Individuals:
Estra-1,3,5(10)-triene-3,17beta-diol diheptanoate is also used in hormone therapy for transgender individuals, particularly for male-to-female (MtF) transitions. It helps in the development of secondary sexual characteristics, such as breast growth, fat redistribution, and softening of the skin, by providing the necessary estrogen levels.
Check Digit Verification of cas no
The CAS Registry Mumber 7732-97-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,7,3 and 2 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 7732-97:
(6*7)+(5*7)+(4*3)+(3*2)+(2*9)+(1*7)=120
120 % 10 = 0
So 7732-97-0 is a valid CAS Registry Number.
7732-97-0Relevant articles and documents
Synthetic technology for oestradiol 17-heptanoate
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Paragraph 0015-0020, (2019/04/04)
The invention discloses a synthetic technology for oestradiol 17-heptanoate, and further provides a preparation method for the oestradiol 17-heptanoate. The method comprises the following steps that 1, 17beta-estradiol serves as a raw material and reacts with heptanoyl chloride under the catalytic action of pyridine so as to obtain 3.17-diheptylic acid-17beta-estradiol; 2, the 3.17-diheptylic acid-17beta-estradiol in the step 1 serves as a raw material, in an alcohol solvent, hydrolysis reaction is carried out under the action of alkaline, and post-treatment is carried out so as to obtain a crude product of the oestradiol 17-heptanoate; and 3, the crude product of the oestradiol 17-heptanoate in the step 2 serves as a raw material, and refining is carried out by adopting methanol so as toobtain a refined product of the oestradiol 17-heptanoate. The preparation method for the oestradiol 17-heptanoate has the advantages that the technological method is simple, the yield of the target product is high, the production cost is low, the generation amount of chemical pollutants is small, and the method is suitable for industrial production.
