77412-11-4

Basic information

• Product Name: 5-methyl-2-(phenylthio)-2-(trimethylsilylmethyl)hexanenitrile
• Synonyms: 5-methyl-2-(phenylthio)-2-(trimethylsilylmethyl)hexanenitrile
• CAS NO: 77412-11-4
• Molecular Weight: 305.56
• Mol File: 77412-11-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-methyl-2-(phenylthio)-2-(trimethylsilylmethyl)hexanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-2-(phenylthio)-2-(trimethylsilylmethyl)hexanenitrile(77412-11-4)
• EPA Substance Registry System: 5-methyl-2-(phenylthio)-2-(trimethylsilylmethyl)hexanenitrile(77412-11-4)

Safety Data

• Hazardous Substances Data: 77412-11-4(Hazardous Substances Data)

Upstream product

• 541-28-6 isopentyl iodide 
• 61829-51-4 2-(phenylthio)-3-(trimethysilyl)propanenitrile 

Downstream Products

• 77412-03-4 6-methyl-3-(phenylthio)-3-(trimethylsilylmethyl)heptan-2-ol 
• 77412-19-2 5-methyl-2-(phenylthio)-2-(trimethylsilylmethyl)hexan-1-ol 
• 77412-06-7 5-methyl-1-(phenylthio)-2-(trimethylsilylmethyl)hex-2-ene 
• 77412-07-8 2-chloro-5-methyl-2-trimethylsilylmethylhexyl phenyl sulphide 
• 77412-05-6 2-(3-methylbutyl)prop-2-en-1-ol 
• 66164-93-0 5-methyl-2-(phenylthiomethyl)hex-1-ene 
• 77412-12-5 5-methyl-2-(phenylthio)-2-(trimethylsilylmethyl)hexanal 

Relevant articles and documents

The Formation of Allyl Sulphides by Phenylthio-migration: Control by Silicon

When γ-silyl-β-phenylthio-alcohols are treated with acid, the strategically placed silyl group encourages the rearrangement of the phenylthio-group, both from a secondary migration origin to a secondary migration terminus, and from a secondary migration origin to a tertiary migration terminus (4)->(6).Geraniol/nerol (12) and linalool (14) have been synthesised from a common intermediate (11) using this type of reaction.Phenylthio-migration from a tertiary migration origin (17)->(3) can be controlled to a limited extent by a suitably placed silyl group, but it is easier to achieve direct β-elimination of the silyl and phenylthio-groups (17)->(18).