774222-38-7Relevant articles and documents
An investigation into the structure-activity relationships associated with the systematic modification of the β2-adrenoceptor agonist indacaterol
Beattie, David,Beer, David,Bradley, Michelle E.,Bruce, Ian,Charlton, Steven J.,Cuenoud, Bernard M.,Fairhurst, Robin A.,Farr, David,Fozard, John R.,Janus, Diana,Rosethorne, Elizabeth M.,Sandham, David A.,Sykes, David A.,Trifilieff, Alexandre,Turner, Katharine L.,Wissler, Elke
, p. 6280 - 6285 (2012/10/30)
The synthesis of a series of indacaterol analogues in which each of the three structural regions of indacaterol are modified in a systematic manner is described. Evaluation of the affinity of these analogues for the β2-adrenoceptor identified t
