774235-34-6

Basic information

• Product Name: 1-[(2,3,5-tri-O-benzoyl-β-D-ribofuranosyloxy)methyl]acetate
• Synonyms: 1-[(2,3,5-tri-O-benzoyl-β-D-ribofuranosyloxy)methyl]acetate
• CAS NO: 774235-34-6
• Molecular Weight: 534.519
• Mol File: 774235-34-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[(2,3,5-tri-O-benzoyl-β-D-ribofuranosyloxy)methyl]acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(2,3,5-tri-O-benzoyl-β-D-ribofuranosyloxy)methyl]acetate(774235-34-6)
• EPA Substance Registry System: 1-[(2,3,5-tri-O-benzoyl-β-D-ribofuranosyloxy)methyl]acetate(774235-34-6)

Safety Data

• Hazardous Substances Data: 774235-34-6(Hazardous Substances Data)

Upstream product

• 14215-97-5 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose 
• 66981-55-3 2-propynyl 2,3,5-tri-O-benzoyl-β-D-ribofuranoside 
• 774235-33-5 2-(oxopropoxy) 2,3,5-tri-O-benzoyl-β-D-ribofuranoside 

Downstream Products

• 774235-40-4 N⁶-acetyl-9-[(2,3,5-tri-O-benzoyl-β-D-ribofuranosyloxy)methyl]guanine 
• 774235-41-5 N⁶-acetyl-7-[(2,3,5-tri-O-benzoyl-β-D-ribofuranosyloxy)methyl]guanine 
• 17494-84-7 N²-acetyl-9-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)guanine 
• 28782-67-4 N²-acetyl-7-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)guanine 
• 774235-39-1 N⁶-benzoyl-9-[(2,3,5-tri-O-benzoyl-β-D-ribofuranosyloxy)methyl]adenine 
• 6984-53-8 N⁶,2',3',5'-tetra-O-benzoyladenosine 
• 774235-37-9 1-[(2,3,5-tri-O-benzoyl-β-D-ribofuranosyloxy)methyl]cytosine 
• 31652-74-1 cytidine 2',3',5'-tri-O-benzoate 
• 774235-36-8 1-[(2,3,5-tri-O-benzoyl-β-D-ribofuranosyloxy)methyl]thymine 
• 774235-35-7 1-[(2,3,5-tri-O-benzoyl-β-D-ribofuranosyloxy)methyl]uracil 
• 1748-04-5 tribenzoyl uridine 

Relevant articles and documents

The synthesis of [(β-D-ribofuranosyloxy)-methyl]nucleosides

The coupling reaction of acetoxymethoxy ribofuranoside 4 with nucleic acid bases 5a-f to synthesize novel (ribofuranosyloxy)methyl uracil, thymine, cytosine, adenine, guanine derivatives 6a-g respectively in preference to the expected formation of natural nucleosides 2′,3′,5′ -tri-O-benzoyl uridine, methyluridine, cytidine, adenosine and guanosine 7a-g is described. Detailed study of these reactions catalysed by Lewis acids TMSOTf and SnCl4 is described. TMSOTf exhibited selectivity for the formation of ribofuranosyloxy methyl derivatives 6a-g rather than 7a-g. Reason for formation of 6a-g is explained by HSAB principle.