77455-52-8

Basic information

• Product Name: 5-(2-chlorophenyl)-1-methyl-1H-tetrazole
• Synonyms: 5-(2-chlorophenyl)-1-methyl-1H-tetrazole
• CAS NO: 77455-52-8
• Molecular Weight: 194.623
• Mol File: 77455-52-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(2-chlorophenyl)-1-methyl-1H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-chlorophenyl)-1-methyl-1H-tetrazole(77455-52-8)
• EPA Substance Registry System: 5-(2-chlorophenyl)-1-methyl-1H-tetrazole(77455-52-8)

Safety Data

• Hazardous Substances Data: 77455-52-8(Hazardous Substances Data)

Upstream product

• 50907-46-5 5-(2-chlorophenyl)-1H-tetrazole 
• 74-88-4 methyl iodide 
• 616-38-6 carbonic acid dimethyl ester 
• 873-32-5 2-Chlorobenzonitrile 
• 3400-31-5 2-chloro-N-methylbenzamide 

Downstream Products

• 1334306-25-0 5-(2-(diphenylphosphino)phenyl)-1-methyl-1H-tetrazole 
• 1415801-88-5 C₂₀H₁₇N₄OP 

Relevant articles and documents

An Environmentally Friendly Method for N-Methylation of 5-Substituted 1H-Tetrazoles with a Green Methylating Reagent: Dimethyl Carbonate

An environmentally friendly method was established for the N-methylation of the 5-substituted 1H-tetrazoles with a green reagent: DMC. DABCO was the optimal catalyst, and hazardous chemicals were avoided in this protocol. A plausible catalytic mechanism is proposed, which consists of a DABCO-activated process and a thermally induced rearrangement of tetrazole carbamates.