77505-89-6Relevant articles and documents
Synthesis of 2-amino-5-arylthiazoles by palladium-catalyzed arylation at the C5 position with aryl iodides
Priego, Julián,Gutiérrez, Sonia,Ferritto, Rafael,Broughton, Howard B.
, p. 2957 - 2960 (2007)
A new synthetic route to afford 2-amino-5-aryl thiazoles has been developed. The starting aminothiazole derivative can be arylated at position 5 with aryl iodides under palladium-catalyzed conditions. Mechanistic studies suggest a proton-abstraction pathw