77510-05-5

Basic information

• Product Name: allyl-(3-phenyl-[1,2,4]thiadiazol-5-yl)-amine
• Synonyms: allyl-(3-phenyl-[1,2,4]thiadiazol-5-yl)-amine
• CAS NO: 77510-05-5
• Molecular Weight: 217.294
• Mol File: 77510-05-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: allyl-(3-phenyl-[1,2,4]thiadiazol-5-yl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: allyl-(3-phenyl-[1,2,4]thiadiazol-5-yl)-amine(77510-05-5)
• EPA Substance Registry System: allyl-(3-phenyl-[1,2,4]thiadiazol-5-yl)-amine(77510-05-5)

Safety Data

• Hazardous Substances Data: 77510-05-5(Hazardous Substances Data)

Upstream product

• 24255-23-0 5-chloro-3-phenyl-[1,2,4]thiadiazole 
• 107-11-9 1-amino-2-propene 
• 61787-75-5 2-(iminophenylmethyl)-1,1,1-trimethylhydrazinium hydroxide inner salt 
• 1670-14-0 benzamidine monohydrochloride 
• 57-06-7 N-allyl isothiocyanate 

Relevant articles and documents

Copper-Catalyzed Aerobic Oxidative [3+2] Annulation for the Synthesis of 5-Amino/Imino-Substituted 1,2,4-Thiadiazoles through C-N/N-S Bond Formation

A copper-catalyzed aerobic oxidative annulation reaction of 2-aminopyridine/amidine with isothiocyanate has been reported. This strategy involving C-N/N-S bond formations provides various 5-amino/imino-substituted 1,2,4-thiadiazole derivatives under a Cu/O2 catalytic system. This method has demonstrated high reactivity, mild reaction conditions, and a broad substrate scope. Furthermore, the synthetic utilities of the approach are demonstrated by further modifications.

Amidrazones. 6(1). Synthesis of 1,2,4-Thiadiazoles by Thermolysis of N3-Thiocarbamoylamidrazone Ylides

Reaction of N3-unsubstituted amidrazone ylides (1a and 1b) with alkyl or aryl isothiocyanates gives N3-thiocarbamoylamidrazone ylides (2).Thermolysis of 2 gives 3-alkyl(or aryl)-5-alkyl(or aryl)amino-1,2,4-thiadiazoles (a-i).