7752-72-9

Basic information

• Product Name: 5-CHLORO-6-METHYLPYRIMIDIN-4(1H)-ONE
• Synonyms: 5-CHLORO-6-METHYLPYRIMIDIN-4(1H)-ONE;4(1H)-Pyrimidinone, 5-chloro-6-methyl- (9CI);5-Chloro-6-MethylpyriMidin-4(3H)-one;4-Chloro-6-methyl-pyrimidin-5-ol;5-Chloro-6-hydroxy-4-methylpyrimidine;5-Chloro-6-methylpyrimidin-4(3H);5-Chloro-6-methyl-1H-pyrimidin-4-one
• CAS NO: 7752-72-9
• Molecular Formula: C₅H₅ClN₂O
• Molecular Weight: 144.56
• Product Categories: PYRIMIDINE
• Mol File: 7752-72-9.mol
• Article Data: 21

Chemical Properties

• Melting Point: 209-211 °C
• Boiling Point: 206.4°C at 760 mmHg
• Flash Point: 78.6°C
• Appearance: /
• Density: 1.45g/cm³
• Vapor Pressure: 0.238mmHg at 25°C
• Refractive Index: 1.608
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 7.70±0.50(Predicted)
• CAS DataBase Reference: 5-CHLORO-6-METHYLPYRIMIDIN-4(1H)-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-6-METHYLPYRIMIDIN-4(1H)-ONE(7752-72-9)
• EPA Substance Registry System: 5-CHLORO-6-METHYLPYRIMIDIN-4(1H)-ONE(7752-72-9)

Safety Data

• Hazardous Substances Data: 7752-72-9(Hazardous Substances Data)

Usage

General Description

5-CHLORO-6-METHYLPYRIMIDIN-4(1H)-ONE is a chemical compound with the molecular formula C5H5ClN2O. It is a pyrimidinone derivative with a chlorine atom at the 5th position and a methyl group at the 6th position. 5-CHLORO-6-METHYLPYRIMIDIN-4(1H)-ONE is commonly used in the synthesis of pharmaceuticals and agrochemicals. It is also used as a building block in the production of various organic compounds. 5-CHLORO-6-METHYLPYRIMIDIN-4(1H)-ONE has potential applications in the pharmaceutical and agricultural industries due to its unique chemical structure and reactivity.

InChI:InChI=1/C5H5ClN2O/c1-3-4(6)5(9)8-2-7-3/h2H,1H3,(H,7,8,9)

Upstream product

• 3524-87-6 6-methyl-3H-pyrimidin-4-one 
• 6710-83-4 formimidamide acetate 
• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 
• 3473-63-0 formamidine acetic acid 
• 463-52-5 formamidine 
• 6313-33-3 formamidine hydrochloride 

Downstream Products

• 83942-10-3 4,5-dichloro-6-methyl-pyrimidine 
• 792909-14-9 5-chloro-6-(chloromethyl)-3H-pyrimidin-4-one 

Relevant articles and documents

SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF

The present invention discloses a substituted pyrimidine compound. The structure is shown in general formula I. The definition of each substituent in the formula is described in the description. The compound of the present invention has broad-spectrum fungicidal, insecticidal and acaricidal activity, and has excellent control effects on cucumber downy mildew, powdery mildew, corn rust, anthrax, rice blast, aphids, Tetranychus cinnabarinus and the like.

Spirocyclic compound containing pyrimidine and application thereof

The invention discloses a pyrimidine-containing spiro compound, structure as shown in a general formula I : The compound of the invention has a broad-spectrum bactericidal activity . and has an excellent control effect, on cucumber downy mildew, wheat powdery mildew, corn rust, rice blast, cucumber anthracnose and the like.

Design, synthesis, insecticidal, and acaricidal activities of novel pyrimidinamine derivatives containing a biphenyl ether

A series of original pyrimidinamine derivatives containing a biphenyl ether moiety were designed and synthesized. Their structures were confirmed by 1H NMR, MS, and elemental analyses. Their insecticidal activities against lepidopteran and hemiptera insects and acaricidal activities were tested. The results of bioassay demonstrated that 9k showed the best activity (LC50 = 2.08 mg/L) against Tetranychus urticae, which is comparable with the positive control, spirotetramat (LC50 = 2.27 mg/L), and 9g showed better activity (LC50 = 0.52 mg/L) against Aphis fabae than the positive control, imidacloprid (LC50 = 1.02 mg/L), and relatively good activity (LC50 = 2.49 mg/L) against T urticae. Their structure-activity relationships indicated that both an ethyl group on the 4-position of the pyrimidine ring and alkyl chain as a para-substituent group of the benzene ring showed good biological activity.