77546-39-5 Usage
Description
TESTOSTERONE-16,16,17-D3 is a labeled form of testosterone, a principal hormone of the testes produced by the interstitial cells. It is a major circulating androgen that is converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone, which is required for normal male sexual differentiation. Additionally, it is converted by aromatization to estradiol. It is classified as a controlled substance and is considered an anabolic steroid and androgen.
Uses
Used in Pharmaceutical Industry:
TESTOSTERONE-16,16,17-D3 is used as a labeled testosterone for research and development purposes. It helps in understanding the biological actions of testosterone and its conversion to dihydrotestosterone in target tissues, which mediates many of the hormone's effects.
Used in Sports and Fitness Industry:
TESTOSTERONE-16,16,17-D3 is used as a controlled substance in the sports and fitness industry to monitor the use of anabolic steroids and ensure fair competition. Its detection helps in identifying athletes who may be using banned substances to enhance their performance.
Used in Hormone Replacement Therapy:
TESTOSTERONE-16,16,17-D3 can be used as a labeled form of testosterone in hormone replacement therapy for men with low testosterone levels. It helps in monitoring the effectiveness of the treatment and ensuring the appropriate dosage is administered.
Used in Research and Diagnostics:
TESTOSTERONE-16,16,17-D3 is used as a research tool in studying the role of testosterone in various physiological processes and its impact on male sexual differentiation and development. It is also used in diagnostic tests to measure testosterone levels in patients and assess any imbalances or deficiencies.
Check Digit Verification of cas no
The CAS Registry Mumber 77546-39-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,5,4 and 6 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 77546-39:
(7*7)+(6*7)+(5*5)+(4*4)+(3*6)+(2*3)+(1*9)=165
165 % 10 = 5
So 77546-39-5 is a valid CAS Registry Number.
77546-39-5Relevant articles and documents
The Selective Protection of the 3-Ketone Functions of Steroids as Heptafluoro-p-tolyl Enol Ethers
Jarman, Michael,McCague, Raymond
, p. 1129 - 1134 (2007/10/02)
Conjugated and unconjugated 3-ketone functions in steroids react with octafluorotoluene at above 100 deg C in the presence of caesium fluoride to give heptafluoro-p-tolyl enol ethers.The related but unusually reactive Wieland-Miescher ketone (11) reacted at room temperature in the presence of tetra-n-butylammonium fluoride.Enones were regenerated from their derivatives by acidic hydrolysis.Hydrolysis of the derivative (10) of 4,5α-dihydroxytestosterone was slu but sodium methoxide regenerated the parent steroid.The methods have been applied in a synthesis of deuterium-labelled testosterone.
