77553-26-5

Basic information

• Product Name: 2,5-diphenyl-3-benzoyl-3a,6a-dihydrofuro<3,2-c>isoxazoline
• Synonyms: 2,5-diphenyl-3-benzoyl-3a,6a-dihydrofuro<3,2-c>isoxazoline
• CAS NO: 77553-26-5
• Molecular Weight: 369.42
• Mol File: 77553-26-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,5-diphenyl-3-benzoyl-3a,6a-dihydrofuro<3,2-c>isoxazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-diphenyl-3-benzoyl-3a,6a-dihydrofuro<3,2-c>isoxazoline(77553-26-5)
• EPA Substance Registry System: 2,5-diphenyl-3-benzoyl-3a,6a-dihydrofuro<3,2-c>isoxazoline(77553-26-5)

Safety Data

• Hazardous Substances Data: 77553-26-5(Hazardous Substances Data)

Upstream product

• 5492-70-6 phenyl-glyoxal-2-(N-phenyl oxime ) 
• 17113-33-6 2-phenylfuran 

Downstream Products

• 77541-50-5 C₂₄H₁₇NO₃ 

Relevant articles and documents

1,3-DIPOLAR CYCLOADDITION OF C-BENZOYL-N-PHENYLNITRONE WITH FURAN DERIVATIVES. ANOMALOUS DEHYDROGENATION OF CYCLOADDUCTS WITH 2,3-DICHLORO-5,6-DICYANO-1,4-BENZOQUINONE

C-Benzoyl-N-phenylnitrone reacted with 2-R-substituted (R=phenyl,CH2OH,CH2OCOCH3,CH2SH)furan derivatives at 55 deg C by a 3-dipolar cycloaddition reaction to the unsubstituted furan double bond to give mono- and bisadducts. 2,5-Dimethylfuran afforded monoadduct only.Dehydrogenations of monoadducts of 5-R-2-phenyl-3-benzoyl-3a,6a-dihydrofuroisoxazolines with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone proceeded anomously at 60 deg C: dehydrogenation followed by electrocyclic opening afforded the corresponding ketonitrones.This method of dehydrogenation offersa new preparation of nitrones and further exemplifies the exploitation of products of 1,3-dipolar cycloaddition for synthetic purposes.