7758-31-8 Usage
Description
BETAINE ALDEHYDE CHLORIDE, also known as Choline Aldehyde Chloride, is an intermediate compound in the enzymatic oxidation of choline to betaine. It is a colorless crystalline solid with unique chemical properties that make it valuable in various applications.
Uses
Used in Pharmaceutical Industry:
BETAINE ALDEHYDE CHLORIDE is used as an intermediate for the enzymatic oxidation of choline to betaine, which plays a crucial role in various biological processes and is essential for the synthesis of trimethylamine oxide in fish.
Used in Chemical Synthesis:
BETAINE ALDEHYDE CHLORIDE is used as a chemical intermediate for the synthesis of various compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals, due to its unique reactivity and properties.
Used in Research and Development:
BETAINE ALDEHYDE CHLORIDE is utilized as a research compound in the development of new methodologies and techniques in organic chemistry, as well as in the study of choline and betaine metabolism and their roles in various biological processes.
Biochem/physiol Actions
Betaine aldehyde is the physiological intermediate in the oxidation of choline to betaine. Mechanistic studies show that in aqueous solution, it exists predominantly (99%) as the diol (hydrate) form.
Check Digit Verification of cas no
The CAS Registry Mumber 7758-31-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,7,5 and 8 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 7758-31:
(6*7)+(5*7)+(4*5)+(3*8)+(2*3)+(1*1)=128
128 % 10 = 8
So 7758-31-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H12NO.ClH/c1-6(2,3)4-5-7;/h5H,4H2,1-3H3;1H/q+1;/p-1
7758-31-8Relevant articles and documents
Synthetic approach for unsaturated precursors for parahydrogen induced polarization of choline and its analogs
Shchepin, Roman V.,Chekmenev, Eduard Y.
, p. 655 - 662 (2014/01/06)
Reported here are (i) a new synthetic approach for preparation of (ii) a new compound class, of -OH, for example, an -OH group is replaced with acetyl protecting group, protected 1,2-dehydrocholine analogs and (iii) a new synthetic route for betaine aldehyde. The C=C bond of 1,2-dehydrocholine moiety can be used for molecular addition of parahydrogen producing -OH protected hyperpolarized choline by parahydrogen-induced polarization (PHIP). The reported synthetic approach allows for incorporation of 15N and deuterium labels, which are necessary for preparation of highly polarized PHIP contrast agents. Isotope labeling with 15N and/or deuterium was conducted. Hyperpolarized 15N-choline enabled by the reported synthetic approach can be potentially used as an imaging biomarker of cancer similar to choline positron emission tomography tracers. Copyright
Isolation and identification of the products of the oxidation of choline.
JELLINEK,STRENGTH,THAYER
, p. 1171 - 1173 (2007/10/05)
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