77650-95-4

Basic information

• Product Name: Proterguride
• Synonyms: Proterguride;1,1-Diethyl-3-(6-propylergolin-8α-yl)urea
• CAS NO: 77650-95-4
• Molecular Formula: C22H32N4O
• Molecular Weight: 368.522
• Mol File: 77650-95-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 133°C
• Boiling Point: 498.83°C (rough estimate)
• Flash Point: 318.4°C
• Appearance: /
• Density: 1.0877 (rough estimate)
• Vapor Pressure: 1.73E-14mmHg at 25°C
• Refractive Index: 1.6500 (estimate)
• CAS DataBase Reference: Proterguride(CAS DataBase Reference)
• NIST Chemistry Reference: Proterguride(77650-95-4)
• EPA Substance Registry System: Proterguride(77650-95-4)

Safety Data

• Hazardous Substances Data: 77650-95-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C22H32N4O/c1-4-10-26-14-16(24-22(27)25(5-2)6-3)12-18-17-8-7-9-19-21(17)15(13-23-19)11-20(18)26/h7-9,13,16,18,20,23H,4-6,10-12,14H2,1-3H3,(H,24,27)/t16-,18+,20+/m0/s1

Upstream product

• 83455-46-3 6-Norterguride 
• 106-94-5 propyl bromide 
• 96860-95-6 (5R, 8S, 10R)-6-propyl-8-ergolinyl isocyanate 
• 109-89-7 diethylamine 
• 99518-36-2 (6aR,9S,10aR)-7-Propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carbonyl azide 
• 96860-91-2 1-<(5R,8S,10R)-6-cyano-8-ergolinyl>-3,3-diethylurea 
• 96860-93-4 (6aR,9S,10aR)-9-(3,3-Diethyl-ureido)-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-7-carboxylic acid 
• 86891-20-5 Hydrazide of (5R,8S,10R)-6-propyl-8-ergolinecarboxylic acid 
• 37686-84-3 terguride 

Relevant articles and documents

Use of 1-(8-alpha-ergolinyl)-3,3-diethyl urea derivatives in the treatment of endometritis

A composition for the treatment of endometritis in mammalian females which comprises as the physiologically active component a 1-(8alpha-ergolinyl)-3,3-diethylurea of the general formula I in which R1 represents an alkyl group containing from 1 to 3 carbon atoms, R2 represents a hydrogen atom or an alkyl group containing from 1 to 3 carbon atoms and either X stands for a hydrogen atom or both of them form jointly an additional bond between carbon atoms in positions 9 and 10, or a pharmaceutically acceptable acid addition salt thereof. The subject composition of the invention is suitable for treating acute puerperal inflammations and chronic endometritis in mammalian females, especially farm animal females, e.g. cows.